Abstract
Objectives To study the CT diagnosis of COVID-19 that was based on the
imaging features of pulmonary lobular structure. Materials and methods
After institutional review board approval and informed consent, 139
cases with suspected COVID-19 who undergone CT were retrospectively
analyzed. Based on the anatomical structure of pulmonary lobule, the
imaging features of pulmonary lobular structure on CT images was defined
and built simulation diagrams serve as a unified standard. The imaging
performance of confirmed 103 cases was evaluated for diagnosis of
COVID-19. Results Of these139 cases, 103 cases were confirmed for
COVID-19, 36 cases were confirmed for other diseases. Of the 103
COVID-19 cases, 82(79.61%) cases were typical cases and
21(20.39%)cases were atypical cases. 65(63.11% ) cases were in the
early or advanced stage, 26(25.24%) cases were in the severe or
recovery stage, and 12(11.65%)were in multiple stages. The scores of
pulmonary lobular structure in typical COVID-19 (3.42±1.25) were
significant different compared with atypical COVID-19 (1.51±1.34,
P<0.001). The inter-observer agreement for the score of
pulmonary lobular structure was excellent (kappa = 0.863,
P<0.05). Conclusion To recognize the CT common imaging signs
of pulmonary lobular structure in COVID-19 can deepen the understanding
of COVID-19 from the basis of image anatomy, and screen suspected cases
and provide imaging basis for diagnosis and differential diagnosis.