loading page

Integration of ceritinib and bevacizumab as a promising treatment strategy for brain metastases from ALK mutation-position non-small cell lung cancer: a case report
  • +5
  • Yinxue Xia,
  • Shuhe Lu,
  • Weixi Shen,
  • Tao Xin,
  • Chengjuan Fan,
  • Chong Teng,
  • Xiaowei Song,
  • Yanju Lv
Yinxue Xia
Harbin Medical University

Corresponding Author:[email protected]

Author Profile
Shuhe Lu
Harbin Medical University
Author Profile
Weixi Shen
Second Affiliated Hospital of Harbin Medical University
Author Profile
Tao Xin
Second Affiliated Hospital of Harbin Medical University
Author Profile
Chengjuan Fan
Second Affiliated Hospital of Harbin Medical University
Author Profile
Chong Teng
Second Affiliated Hospital of Harbin Medical University
Author Profile
Xiaowei Song
Second Affiliated Hospital of Harbin Medical University
Author Profile
Yanju Lv
Second Affiliated Hospital of Harbin Medical University
Author Profile

Abstract

Ceritinib shows efficacy in ALK+ NSCLC patients with BM. However, the disease will inevitably progress over time due to acquired resistance. We now report a case with BM from advanced lung adenocarcinoma with ALK mutations who exhibited a surprising and long-term response to treatment of ceritinib combined with bevacizumab.