For all my heavy computing/typing needs, I use a 15" MacBook Pro. For a long time I was opposed to using a Mac, but almost everyone in the astronomy community uses one, so eventually I gave in so that I can more easily use astronomy software. Of course, I need to be able to do calculations, but I also have a bit of a tendon condition in my writing hand. To make things easier on my wrist, I use a Pilot Vanishing Fountain Pen in a Moleskine notebook or glossy magazine paper.