CONCLUSION
CPGs produced by CENETEC during this period had a low score by AGREE II standards and low adherence to the GRADE framework. Improving the training of methodologists in the GRADE methodology and addressing the specific pitfalls in the guidelines development process that we have highlighted should be a priority for CENETEC guidelines process. Enhancing the developer’s capacity and the guidelines quality will result in better and more trustworthy guideline to be used in Mexico
CONFLICT OF INTEREST: The authors declared that they do not have financial conflicts of interest. Also, none of the authors are part of CENETEC organization. RN, IDF and GG are members of the GRADE working group. IDF is part of the AGREE collaboration.