Conclusion
HFpEF is a complex clinical entity mediated by multiple clinical factors
leading to various structural alterations. Risk factor exposure leads to
an evolution of abnormal myocardial mechanics in each cardiac chamber.
Initially, many deformation parameters only deteriorate during exercise.
Although common mechanical changes are often present, significant
heterogeneity in structure and function may exist. In addition to
multiple imaging biomarkers, heterogeneity of clinical features and
associated medical conditions compound this syndromes complexity.
Current methods resort to an oversimplified approach for assessment and
risk stratification. With the evolution of technology and computer
capabilities, artificial intelligence (AI) is opening new frontiers in
cardiovascular imaging. This technology can be integrated with diastolic
indices and speckle tracking echocardiography to offer innovative
insights into HFpEF 52.