Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection has become a pandemic cause of viral pneumonia. Elderly patients with chronic comorbidities are susceptible to SARS-CoV-2, and are more likely to have complications that can lead to severe or even fatal consequences. It is important to seek the appropriate effective treatment for these susceptible persons. Here we report a case of elderly COVID-19 patient with hypertension, which was a member of the familial cluster COVID-19 in Enshi City, Hubei Province, China. He successfully survived after removal of tracheal intubation and inhalation of the invasive mechanical ventilation (IMV). This report aims to provide an inspiration for the prevention and treatment of critical COVID-19 cases.