|
|
Severe Group |
Non-Severe Group |
|
|
|
Demography characteristic |
Demography characteristic |
Demography
characteristic |
Demography characteristic |
Demography characteristic |
Demography characteristic |
Demography characteristic |
Age |
14 |
771 |
1795 |
11.12 [6.70, 15.55] |
P<0.0001; I²
=92% |
P<0.00001 |
Sex (male, year) |
12 |
409 in 747 (54.8%) |
843 in 1724 (48.9%) |
1.30 [1.07, 1.57] |
P= 0.62; I² = 0% |
P=0.007 |
Comorbidity |
Comorbidity |
Comorbidity |
Comorbidity |
Comorbidity |
Comorbidity |
Comorbidity |
Hypertension |
7 |
166 in 497(33.4%) |
151 in 973(15.5 %) |
2.30
[1.35, 3.92] |
P=0.03; I²= 57% |
P=0.002 |
Diabetes |
7 |
88 in 497(17.7%) |
65 in 973(6.7%) |
2.62 [1.27,
5.44] |
P=0.02; I²= 61% |
P=0.009 |
Heart Disease |
7 |
46 in 497 (9.3%) |
29 in 973 (3.0%) |
4.02
[2.08, 7.77] |
P=0.29; I² = 18% |
P<0.0001 |
Cerebrovascular Disease |
2 |
10 in 344(2.9%) |
4 in 248(1.6%) |
1.81
[0.56, 5.84] |
P=0.66; I² = 0% |
P=0.32 |
COPD |
5 |
20 in 492(4.1%) |
4 in 598(0.7%) |
4.20 [1.61, 10.95] |
P=0.42; I² = 0% |
P=0.003 |
Chconic live disease |
4 |
13 in 476(2.7%) |
30 in 883(3.4%) |
1.28
[0.60, 2.71] |
P=0.45; I² = 0% |
P=0.53 |
Chronic kidney disease |
4 |
12 in 476(2.5%) |
10 in 883(1.1%) |
2.12
[0.80, 5.61] |
P=0.34; I²= 11% |
P=0.13 |
Tuberculosis |
2 |
9 in 344(2.6%) |
2 in 248(0.8%) |
2.69 [0.66,
10.97] |
P=0.47; I² = 0% |
P=0.17 |
Smoke |
4 |
16 in 433(3.7%) |
49 in 781(6.3%) |
1.07 [0.40, 2.85] |
P=0.12; I²= 48% |
P=0.90 |
Any |
4 |
226 in 398(56.8%) |
137 in 430(31.9%) |
3.61 [1.62,
8.01] |
P=0.003; I² = 78% |
P=0.002 |
Signs and Symptoms |
Signs and Symptoms |
Signs and Symptoms |
Signs and
Symptoms |
Signs and Symptoms |
Signs and Symptoms |
Signs and
Symptoms |
Fever |
9 |
552 in 593(93.1%) |
795 in 957(83.1%) |
1.93 [0.94,
3.96] |
P=0.007; I² = 62% |
P=0.07 |
Expectoration |
4 |
144 in 379(38.0%) |
94 in 370(25.4%) |
1.79
[0.79, 4.05] |
P=0.02; I²= 69% |
P=0.17 |
Headache |
4 |
56 in 397(14.1%) |
56 in 525(10.7%) |
1.43 [0.91,
2.26] |
P=0.74; I² = 0% |
P=0.12 |
Fatigue |
4 |
210 in 396(53.0%) |
189 in 522(36.2%) |
1.75 [0.89,
3.44] |
P=0.02; I² = 69% |
P=0.11 |
Myalgia |
3 |
114 in 394(28.9%) |
70 in 421(16.6%) |
2.22 [0.65,
7.52] |
P<0.0001; I² = 90% |
P=0.20 |
Dyspnea |
5 |
82 in 192(42.7%) |
52 in 477(10.9%) |
7.83 [1.75,
34.99] |
P<0.0001; I²=86% |
P=0.007 |
Laboratory test(x10⁹ per L) |
Laboratory test(x10⁹ per L) |
Laboratory
test(x10⁹ per L) |
Laboratory test(x10⁹ per L) |
Laboratory test(x10⁹
per L) |
Laboratory test(x10⁹ per L) |
Laboratory test(x10⁹ per
L) |
Leucocytes count |
6 |
518 |
649 |
0.65 [-1.02, 2.32] |
P<0.0001;I²=94% |
P=0.44 |
Neutrophils count |
6 |
483 |
601 |
0.33 [-0.66, 1.33] |
P<0.0001;I²=94% |
P=0.51 |
Lymphocyte count |
7 |
539 |
683 |
-0.42 [-0.64, -0.20] |
P<0.0001; I² = 92% |
P=0.0002 |
Monocyte count |
3 |
384 |
391 |
0.01 [-0.06, 0.09] |
P = 0.05; I² =
66% |
P=0.70 |
Image feature in chest CT |
Image feature in chest CT |
Image feature in
chest CT |
Image feature in chest CT |
Image feature in chest CT |
Image
feature in chest CT |
Image feature in chest CT |
Bilateral pneumonia |
5 |
162 in 219(95.8%) |
378 in 515(73.4%) |
1.48
[0.50, 4.35] |
P=0.09; I² = 53% |
P=0.48 |
Unilateral pneumonia |
3 |
47 in 154(30.5%) |
99 in 362(27.3%) |
0.98
[0.40, 2.42] |
P =0.18; I² = 42% |
P=0.97 |
Ground-glass opacities |
2 |
39 in 39(100%) |
129 in 145(89.0%) |
3.71
[0.45, 30.23] |
P = 0.66; I² = 0% |
P=0.22 |
Consolidation |
2 |
30 in 39(76.9%) |
67 in 145(46.2%) |
3.32 [1.00,
11.03] |
P = 0.17; I² = 48% |
P=0.05 |
Reticulation |
2 |
12 in 39(30.8%) |
40 in 145(27.9%) |
2.86 [1.01,
8.14] |
P = 0.34; I² = 0% |
P<0.05 |
Bronchial wall thickening |
2 |
22 in 39(56.4%) |
25 in 145(16.0%) |
8.23 [0.59, 115.05] |
P = 0.004; I² = 88% |
P=0.12 |
Intrathoracic lymph node enlargement |
2 |
8 in 39(20.5%) |
0 in
145(0%) |
31.90 [3.65, 278.98] |
P = 0.67; I² = 0% |
P=0.002 |
Pleural effusions |
2 |
12 in 39(30.8%) |
9 in 145(6.2%) |
10.84
[1.07, 109.80] |
P = 0.13; I² = 57% |
P=0.04 |
OR= odds ratio; WMD=weighted mean difference; 95%CIs+95% confidence
intervals; COPD= chronic obstructive pulmonary disease. |
OR= odds
ratio; WMD=weighted mean difference; 95%CIs+95% confidence intervals;
COPD= chronic obstructive pulmonary disease. |
OR= odds ratio;
WMD=weighted mean difference; 95%CIs+95% confidence intervals; COPD=
chronic obstructive pulmonary disease. |
OR= odds ratio; WMD=weighted
mean difference; 95%CIs+95% confidence intervals; COPD= chronic
obstructive pulmonary disease. |
OR= odds ratio; WMD=weighted mean
difference; 95%CIs+95% confidence intervals; COPD= chronic obstructive
pulmonary disease. |
OR= odds ratio; WMD=weighted mean difference;
95%CIs+95% confidence intervals; COPD= chronic obstructive pulmonary
disease. |
OR= odds ratio; WMD=weighted mean difference; 95%CIs+95%
confidence intervals; COPD= chronic obstructive pulmonary
disease. |