Conclusion
This case highlights the importance of keeping a high suspicion and
diagnosing the pathology at the earliest to treat and control the
disease in these critically ill patients. Though they may be
immunocompetent and with no risk factors prior to admission to the ICU,
they become vulnerable and the risk of developing primary/latent CMV
infection is high. A timely diagnosis can prevent prolonged ICU and
hospital stay. It also warrants judicious use of corticosteroids and
other immunomodulatory drugs like tocilizumab in critically ill
patients. In the present Scenario, while treating patients with COVID-19
with the use of immunosuppressive therapy should be justified while
being alert for signs and symptoms of CMV reactivation. Early
recognition of CMV infection and initiation of early treatment will
prevent life-threatening bleeding and mortality.