3.2 Detection of DRPs
As shown in Table 2, a total of 525 DRPs were identified during the
study period. An average of 2.15 DRPs per patient was detected.
Treatment effectiveness P1 (53.71%) was the most common problems of
DRPs followed by treatment safety (33.90%). The main causes of DRPs
were related to drug selection (71.43%) and dose selection (20.57%).
These identified DRPs led to interventions proposed to prescribers in
96.19% of the cases. The most frequently recommended intervention was
changing the drug (48.76%), followed by changing the dosage (24.76%)
and starting a drug (11.62%). These interventions were accepted by the
patients in 92.38% of the cases and were completely implemented in
90.48%.
The univariate analysis showed that the “number of drugs” and “number
of chronic conditions” were the significant factors affecting the
number of DRPs. In the multivariate analysis, only “number of drugs”
was associated with the number of DRPs (P <0.0001), as described
in Table 3.