General recommendations on the provision of biologics in an ENT setting
Biologics should be available only in a designated specialist centres that can offer appropriate alternative interventions
Specialist centres should be co-located with Severe Asthma clinics that are already providing biologic therapies.
A CT scan is required to establish extent of disease and that of previous surgery
Endoscopic confirmation is essential in the assessment of eligibility and response
Revision surgery should be considered prior to a biologic if the previous surgery was a polypectomy without opening the sinuses
Until there is evidence to support the safety and efficacy of biologics in CRS without nasal polyps, biologics should NOT be prescribed
Outside of the NHS, self-paying patients with CRSwNP may select biologic therapies as an alternative to surgery or OCS provided that they have been given information regarding the risks and benefits of each option