6. Conclusions and Clinical Implications
Drug challenge induced Type-1 Brugada pattern in symptomatic patients has similar incidence of MAE when compared to spontaneous Type-1 Brugada pattern. However, the incidence of MAE in drug challenge induced Type-1 Brugada pattern in asymptomatic patients is very low. A positive drug challenge testing is not a good predictor of MAE in asymptomatic patient. Ventricular tachyarrhythmia during drug challenge testing could be a useful marker of risk for MAE in patients with Brugada syndrome.