6. Conclusions and Clinical Implications
Drug
challenge induced Type-1 Brugada pattern in symptomatic patients has
similar incidence of MAE when compared to spontaneous Type-1 Brugada
pattern. However, the incidence of MAE in drug challenge induced Type-1
Brugada pattern in asymptomatic patients is very low. A positive drug
challenge testing is not a good predictor of MAE in asymptomatic
patient. Ventricular tachyarrhythmia during drug challenge testing could
be a useful marker of risk for MAE in patients with Brugada syndrome.