2-2- SARS-CoV-2 pathogen detection
Respiratory samples, including the nasopharyngeal and throat swabs, were obtained from the enrolled patients. The SARS-CoV-2 primary detections were performed using the standard real-time PCR method recommended by CDC using Rotor-Gene-Q 6000 thermocycler (Corbett, Australia) according to the recommended protocol 20. After the SARS-CoV-2 was confirmed in cases, the samples were stored in -70ÂșC for further analysis.