Conclusion
Primary spinal epidural DLBCL is one of the rarest tumors due to which
its diagnosis is challenging. Signs and symptoms are similar to those of
any other epidural space-occupying lesions and thus, can be frequently
misdiagnosed. Back pain with sudden neurological deterioration in lower
limbs should raise the suspicion of rarer diseases like primary spinal
epidural DLBCL. A high degree of suspicion along with team approach
(surgeons, radiotherapist, oncologist, and pathologist) is vital for its
diagnosis and management.