Subjects and specimens
This study was approved by the Ethics Committee of Tongji Hospital and written informed consents were obtained from all subjects. A total of 78 NP patients and 49 control subjects were recruited in this study. The diagnosis of NPs was made according to the current guideline.1 Patients undergoing septoplasty owing to anatomic variations and without any other inflammatory sinonasal disorders were enrolled as control subjects. During surgery, polyp tissues from patients with NPs and inferior turbinate mucosal tissues from control subjects were collected. Not all samples were included in every experiment protocol because of limited quantity. More information is provided in this article’s Online Supplement including Table E1.