The health crisis due to coronavirus disease 2019 (COVID-19) shocks the world with more than million infections and casualties. COVID-19 could present from mild illness to multi-organ involvement, especially acute respiratory distress syndrome. Cardiac injury and arrhythmias including atrial fibrillation (AF) are not uncommon in COVID-19. COVID-19 is highly contagious, and the therapy against the virus remains premature and largely unknown. These make the management of AF patients during pandemic particularly challenging. We here describe possible pathophysiology link between COVID-19 and AF, and therapeutic considerations for AF patients during this pandemic.