Main outcome measures
Women were classified as CH if they had pre-pregnancy hypertension or
had BP ≥140/90 mmHg on two consecutive clinical visits prior to 20
weeks’ gestation in the absence of renal or liver
disease.15 Preeclampsia was defined according to the
International Society for the Study of Hypertension in Pregnancy
(ISSHP)15 as the presence of hypertension along with
at least one of the following: renal involvement (proteinuria ≥300
mg/24h and/or creatinine ≥90 µmol/L or 1 mg/dL), liver impairment
(transaminases >70 IU/L), neurological complications (e.g.
eclampsia), thrombocytopenia (platelet count <150,000/µL).