Main outcome measures
Women were classified as CH if they had pre-pregnancy hypertension or had BP ≥140/90 mmHg on two consecutive clinical visits prior to 20 weeks’ gestation in the absence of renal or liver disease.15 Preeclampsia was defined according to the International Society for the Study of Hypertension in Pregnancy (ISSHP)15 as the presence of hypertension along with at least one of the following: renal involvement (proteinuria ≥300 mg/24h and/or creatinine ≥90 µmol/L or 1 mg/dL), liver impairment (transaminases >70 IU/L), neurological complications (e.g. eclampsia), thrombocytopenia (platelet count <150,000/µL).