Food allergy and overall risk of atopic disorders
There were no food allergy or food sensitization studies identified that
examined fiber or prebiotic interventions. We identified 2
interventional studies of prebiotic supplementation in healthy infants
reporting on general allergic outcomes. No difference in allergic
outcomes at 5 years of age were noted among healthy infants given either
non-hydrolyzed cow milk-based formula supplemented with neutral sc-GOS,
lcFOS, pAOS, and compared to non-supplemented formula or breastfed
children before the age of 8 weeks of life.58 However,
healthy day-care children aged between 1-4 years given a cow’s
milk-based beverage (CMBB) supplemented with docosahexaenoic acid,
polydextrose, GOS, and yeast β-glucan, and additionally fortified with
micronutrients (zinc, vitamin A, iron), 3 times/day for 28 weeks had
fewer episodes of allergic manifestations in the skin and the
respiratory tract, including allergic rhinitis or conjunctivitis,
wheezing, allergic cough, eczema and urticaria (HR 0.64; CI 95% 0.47,
0.89; p=0.007).59