Table 2: Concurrent medications prescribed among the acute coronary syndrome patients receiving two different high-intensity atorvastatin doses (N=626) Table 2: Concurrent medications prescribed among the acute coronary syndrome patients receiving two different high-intensity atorvastatin doses (N=626) Table 2: Concurrent medications prescribed among the acute coronary syndrome patients receiving two different high-intensity atorvastatin doses (N=626) Table 2: Concurrent medications prescribed among the acute coronary syndrome patients receiving two different high-intensity atorvastatin doses (N=626) Table 2: Concurrent medications prescribed among the acute coronary syndrome patients receiving two different high-intensity atorvastatin doses (N=626) Table 2: Concurrent medications prescribed among the acute coronary syndrome patients receiving two different high-intensity atorvastatin doses (N=626)
Medication Class
All Patients (N=626) n (%) Atorvastatin 40mg Users (N= 475) n (%) Atorvastatin 40mg Users (N= 475) n (%) Atorvastatin 80mg Users (N=151) n (%)
P-value
Aspirin 626 (100.0) 475 (100.0) 475 (100.0) 151 (100.0)
P2Y12 inhibitor 623 (99.5) 472 (99.4) 472 (99.4) 151 (100.0) 1.0*
List of P2Y12 inhibitors 0.011*
Clopidogrel
565 (90.3)
437 (92.0)
437 (92.0)
128 (84.8)
Ticagrelor
58 (9.3)
35 (7.4)
35 (7.4)
23 (15.2)
ACE inhibitor or ARB 440 (70.3) 339 (71.4) 339 (71.4) 101 (66.9) 0.294
List of ACE inhibitors 0.916*
Lisinopril
240 (38.3)
185 (38.9)
185 (38.9)
55 (36.4)
Enalapril
12 (1.9)
9 (1.9)
9 (1.9)
3 (2.0)
Ramipril
117 (18.7)
91 (19.2)
91 (19.2)
26 (17.2)
Perindopril
37 (5.9)
27 (5.7)
27 (5.7)
10 (6.6)
Fosinopril
1 (0.2)
1 (0.2)
1 (0.2)
0
List of ARBs 0.435*
Valsartan
33 (5.3)
27 (5.7)
27 (5.7)
6 (4.0)
Losartan
5 (0.8)
5 (1.1)
5 (1.1)
0
Irbesartan
4 (0.6)
2 (0.4)
2 (0.4)
2 (1.3)
Candesartan
1 (0.2)
1 (0.2)
1 (0.2)
0
Beta-blocker 577 (92.2) 433 (91.2) 433 (91.2) 144 (95.4) 0.094
List of beta-blockers 0.660*
Bisoprolol
317 (50.6)
237 (49.9)
237 (49.9)
80 (53.0)
Metoprolol
256 (40.9)
193 (40.6)
193 (40.6)
63 (41.7)
Carvedilol
7 (1.1)
6 (1.3)
6 (1.3)
1 (0.7)
Atenolol
1 (0.2)
1 (0.2)
1 (0.2)
0
Ivabradine 11 (1.8) 7 (1.5) 7 (1.5) 4 (2.6) 0.504*
Nitrate 195 (31.2) 156 (32.8) 156 (32.8) 39 (25.8) 0.206*
*P-value was calculated using Fisher’s Exact test; ACE: angiotensin converting enzyme; ARB: angiotensin II receptor blocker *P-value was calculated using Fisher’s Exact test; ACE: angiotensin converting enzyme; ARB: angiotensin II receptor blocker *P-value was calculated using Fisher’s Exact test; ACE: angiotensin converting enzyme; ARB: angiotensin II receptor blocker *P-value was calculated using Fisher’s Exact test; ACE: angiotensin converting enzyme; ARB: angiotensin II receptor blocker *P-value was calculated using Fisher’s Exact test; ACE: angiotensin converting enzyme; ARB: angiotensin II receptor blocker *P-value was calculated using Fisher’s Exact test; ACE: angiotensin converting enzyme; ARB: angiotensin II receptor blocker