Pathogenesis:
The core pathogenesis that describes COVID-19 infection as the virus that targets the respiratory system with rigorous pneumonia, joint as by means of the occurrence of ground-glass opacities, RNAaemia, along with the cardiac injury that is cute in nature Shen, C et al (2020). Considerably higher levels of the cytokines along with chemokines in blood were eminent in the patients having COVID-19 infection and these included as IL7 IL1RA, IL8, IL1-β, IL9 and IL10 basic, GMCSF, IP10, GCSF, IFNγ, MIP1α, MCP1, PDGFB, MIP1β, TNFα, in addition to the VEGFA Dong, L et al (2020). The severe cases those who were in intensive care unit (ICU) also appeared with the elevated levels of the pro-inflammatory cytokines as those of the, IL7, IL2, IL10, IP10, GCSF, MCP1, MIP1α, as well as TNFα that are rational to endorse the severity of the disease Sanders, J et al (2020). The pathogenesis which explains the biological process or mechanism which leads to the disease state. The Patients tainted through COVID-19 showed to have the elevated numbers of the leukocyte as well as the anomalous findings of the respiratory tract, furthermore augmented levels as of the pro-inflammatory types of cytokines in the plasma Luo, P et al (2020). Some of the COVID-19 patients reports give the conclusion as present with fever with those of cough loutish breathing sounds in both the lungs, along with the temperature of body as about 39.0 °C. The sputum of the patient presented with the positive synchronized polymerase chain reaction consequences so as to confirm the infection of COVID-19 Ren, J et al (2020).The laboratory investigation showed the results with the appearance leucopenia by means of the leukocyte counts of about 2.90 × 10^9 cells/L of which about seventy percent were the WBC type neutrophils. Furthermore, the elevated level of the C-reactive protein as with the value of about 16.16 mg/L which is exceeding the standard range of this C-reactive protein(0–10 mg/L). Also the elevated ESR (erythrocyte sedimentation rate) as well as the D-dimer was also pragmatic Wan, S et al (2020).