Country Design Setting Participants Diagnosis of EjD Cut-offs for serum TSH measurement Intervention Funding
Culha MG (Culha et al., 2020) Turkey Case series (prospective) Hospital Acquired PE sufferers ISSM definition Not stated no none
Khan HL(Khan et al., 2018) Pakistan Case-control study Hospital PE with Diabetes mellitus vs. non-PE (control) DSM-4TR definition and estimated IELT ( with 3 min cut-off) 0.4-4.5 mcIU/ml no none
Canat L (Canat, Erbin, Canat, Dinek, & Çaşkurlu, 2017) Turkey Case-control study Hospital PE sufferers without ED vs. non-PE (control) PEDT Not stated no none
Öztürk MI (Öztürk et al., 2012) Turkey Case-control study Hospital PE patients vs. non-PE (control) Measured IELT 0.4-4 mIU/L no none
Corona G (G Corona et al., 2011) Italy Retrospective cohort Hospital PE or DE sufferers following admission to sexual health unit Study specific PRO for EjD and estimated IELT TSH < 0.2 mIU/L for hyperthyroidism no none
Cihan A (Cihan, Demir, et al., 2009) Turkey Prospective cohort Hospital Hyperthyroid male patients who admitted to Endocrinology outpatient clinic DSM-4TR and measured IELT 0.4mcIU/ml cut-off for Hyperthyroid-ism Specific treatment of hyperthyroidism with medication, surgery or RAI none
Carani C (Carani et al., 2005)
Italy
Prospective cohort
Hospital
Hyperthyroid and Hypothyroid male patients who admitted to Endocrinology clinic
DSM-4TR and measured IELT
0.3-5.0 mcIU/ml
Medical tx of thyroid dysfunction (Metimazole, L-Thyroxine plus Propanolol and Benzodiazepine’s in some cases)
yes
Waldinger MD (Waldinger et al., 2005) Netherlands Case series (prospective) Hospital Patients who admitted to Andrology Unit recruited according to presence of lifelong PE and absence ED Estimated IELT 0.3 -4.0 mcIU/ml no none
Corona G (G. Corona et al., 2004) Italy Cross-sectional Hospital Patients who admitted to sexual health unit Study specific PRO for PE TSH < 0.2 mIU/L for hyperthyroid-ism no yes
Abbreviations Abbreviations Abbreviations Abbreviations Abbreviations Abbreviations Abbreviations Abbreviations Abbreviations
DE: DE: DE: Delayed ejaculation Delayed ejaculation Delayed ejaculation Delayed ejaculation Delayed ejaculation Delayed ejaculation
ED: ED: ED: Erectile dysfunction Erectile dysfunction Erectile dysfunction Erectile dysfunction Erectile dysfunction Erectile dysfunction
EjD: EjD: EjD: Ejaculatory dysfunction Ejaculatory dysfunction Ejaculatory dysfunction Ejaculatory dysfunction Ejaculatory dysfunction Ejaculatory dysfunction
IELT: IELT: IELT: Intra-vaginal ejaculation latency time Intra-vaginal ejaculation latency time Intra-vaginal ejaculation latency time Intra-vaginal ejaculation latency time Intra-vaginal ejaculation latency time Intra-vaginal ejaculation latency time
PE: PE: PE: Premature ejaculation Premature ejaculation Premature ejaculation Premature ejaculation Premature ejaculation Premature ejaculation
PRO: PRO: PRO: Patient reported outcome Patient reported outcome Patient reported outcome Patient reported outcome Patient reported outcome Patient reported outcome
PEDT: PEDT: PEDT: Premature ejaculation diagnostic tool Premature ejaculation diagnostic tool Premature ejaculation diagnostic tool Premature ejaculation diagnostic tool Premature ejaculation diagnostic tool Premature ejaculation diagnostic tool
RAI: RAI: RAI: Radioactive Iodine Radioactive Iodine Radioactive Iodine Radioactive Iodine Radioactive Iodine Radioactive Iodine
TSH: TSH: TSH: Thyroid stimulating hormone Thyroid stimulating hormone Thyroid stimulating hormone Thyroid stimulating hormone Thyroid stimulating hormone Thyroid stimulating hormone