Variable
All patients N=107 courses Medical N=63 courses Surgical N=44 courses P-value (medical vs. surgical)
Patients switched from IV to oral antimicrobial within 24 hours of meeting IV-oral-switch criteria, n (%) 61 (57.0) 35 (55.5) 26 (59.0) 0.71a
Duration (days) of IV antimicrobial, median (IQR) 3.0 (2.25 to 5.00) 3.0 (2.25 to 5.00) 3.0 (2.75 to 4.50) 0.44b
Time delay to switch (days), median (IQR) 0 (0 to 1.25) 0 (0 to 1.75) 0 (0 to 1.00) 0.55b
Time delay (days) to switch in subgroup that did not switch within 24 hours of meeting switch criteria, median (IQR)
1.75 (1.00 to 2.25) (n=46) 2.0 (1.00 to 2.75) (n=28) 1.25 (1.00 to 2.00) (n=18)
0.30b
Patients prescribed an inappropriate choice oral alternative after switching, n (%)
14 (13.2) (n=106) * 9 (14.3%) (n=63) 5 (11.6%) (n=43)
0.69a
Total duration (days) of antimicrobial therapy (IV plus oral), median (IQR)
9.0 (7.00 to 12.75) (n=105) ^ 9.5 (7.00 to 12.25) (n=61) 9.5 (7.25 to 12.75) (n=44)
0.69b
Proportion of courses where the total duration of therapy (IV plus oral) exceeded the recommended duration by >1.0 day, n (%)
47/105 (44.8%) (n=105) ^ 22 (36.1%) (n=61) 25 (56.8%) (n=44)
0.03a
a Chi-square test; bMann-Whitney U-test. Statistical significance was set at p <0.05. * Denominator is 106 because one eligible patient was not switched to oral therapy. ^ Denominator is 105 because two patients were switched to prolonged oral therapy. a Chi-square test; bMann-Whitney U-test. Statistical significance was set at p <0.05. * Denominator is 106 because one eligible patient was not switched to oral therapy. ^ Denominator is 105 because two patients were switched to prolonged oral therapy. a Chi-square test; bMann-Whitney U-test. Statistical significance was set at p <0.05. * Denominator is 106 because one eligible patient was not switched to oral therapy. ^ Denominator is 105 because two patients were switched to prolonged oral therapy. a Chi-square test; bMann-Whitney U-test. Statistical significance was set at p <0.05. * Denominator is 106 because one eligible patient was not switched to oral therapy. ^ Denominator is 105 because two patients were switched to prolonged oral therapy. a Chi-square test; bMann-Whitney U-test. Statistical significance was set at p <0.05. * Denominator is 106 because one eligible patient was not switched to oral therapy. ^ Denominator is 105 because two patients were switched to prolonged oral therapy.