Results
One hundred and sixty-one IV antimicrobial courses of ≥48-hour duration
were screened, with 107 courses in 107 patients eligible for the study
(Figure 1). Characteristics of patients and antimicrobial use are shown
in Table 1.
IV-oral-switch occurred within 24 hours of meeting switch criteria in
61/107 (57%) patients. The median duration of IV antimicrobial courses
before IV-oral-switch was 3 days (IQR, 2.25 to 5.0). The median delay to
switching was 0 days (IQR 0 to 1.25). In the patients who did not
receive timely IV-oral-switch (n =46), the median delay to
switching was 1.75 days (IQR 1.0 to 2.25). Data on primary and secondary
outcomes measures, and comparisons between medical and surgical
patients, are shown in the Table 2.