Results
One hundred and sixty-one IV antimicrobial courses of ≥48-hour duration were screened, with 107 courses in 107 patients eligible for the study (Figure 1). Characteristics of patients and antimicrobial use are shown in Table 1.
IV-oral-switch occurred within 24 hours of meeting switch criteria in 61/107 (57%) patients. The median duration of IV antimicrobial courses before IV-oral-switch was 3 days (IQR, 2.25 to 5.0). The median delay to switching was 0 days (IQR 0 to 1.25). In the patients who did not receive timely IV-oral-switch (n =46), the median delay to switching was 1.75 days (IQR 1.0 to 2.25). Data on primary and secondary outcomes measures, and comparisons between medical and surgical patients, are shown in the Table 2.