Patients switched from IV to oral antimicrobial within 24 hours of
meeting IV-oral-switch criteria, n (%) |
61 (57.0) |
35 (55.5) |
26
(59.0) |
0.71a
|
Duration (days) of IV antimicrobial, median (IQR) |
3.0 (2.25 to 5.00) |
3.0 (2.25 to 5.00) |
3.0 (2.75 to 4.50) |
0.44b
|
Time delay to switch (days), median (IQR) |
0 (0 to 1.25) |
0 (0 to
1.75) |
0 (0 to 1.00) |
0.55b
|
Time delay (days) to switch in subgroup that did not switch within 24
hours of meeting switch criteria, median (IQR)
|
1.75 (1.00 to 2.25)
(n=46)
|
2.0 (1.00 to 2.75)
(n=28)
|
1.25 (1.00 to 2.00)
(n=18)
|
0.30b
|
Patients prescribed an inappropriate choice oral alternative after
switching, n (%)
|
14 (13.2)
(n=106) *
|
9 (14.3%)
(n=63)
|
5 (11.6%)
(n=43)
|
0.69a
|
Total duration (days) of antimicrobial therapy (IV plus oral), median
(IQR)
|
9.0 (7.00 to 12.75)
(n=105) ^
|
9.5 (7.00 to 12.25)
(n=61)
|
9.5 (7.25 to 12.75)
(n=44)
|
0.69b
|
Proportion of courses where the total duration of therapy (IV plus oral)
exceeded the recommended duration by >1.0 day, n (%)
|
47/105 (44.8%)
(n=105) ^
|
22 (36.1%)
(n=61)
|
25 (56.8%)
(n=44)
|
0.03a
|
a Chi-square test; bMann-Whitney
U-test. Statistical significance was set at p <0.05.
* Denominator is 106 because one eligible patient was not switched to
oral therapy.
^ Denominator is 105 because two patients were switched to prolonged
oral therapy.
|
a Chi-square test; bMann-Whitney
U-test. Statistical significance was set at p <0.05.
* Denominator is 106 because one eligible patient was not switched to
oral therapy.
^ Denominator is 105 because two patients were switched to prolonged
oral therapy.
|
a Chi-square test; bMann-Whitney
U-test. Statistical significance was set at p <0.05.
* Denominator is 106 because one eligible patient was not switched to
oral therapy.
^ Denominator is 105 because two patients were switched to prolonged
oral therapy.
|
a Chi-square test; bMann-Whitney
U-test. Statistical significance was set at p <0.05.
* Denominator is 106 because one eligible patient was not switched to
oral therapy.
^ Denominator is 105 because two patients were switched to prolonged
oral therapy.
|
a Chi-square test; bMann-Whitney
U-test. Statistical significance was set at p <0.05.
* Denominator is 106 because one eligible patient was not switched to
oral therapy.
^ Denominator is 105 because two patients were switched to prolonged
oral therapy.
|