Study objective
This study was undertaken to characterize the outcomes and complications of thrombolytic therapy for pediatric thrombosis at our tertiary care center. We also sought to compare patient outcomes when different interventional approaches were used: CDT via an indwelling venous catheter versus bolus tPA administration “on-table” during a single interventional procedure without subsequent catheter-directed tPA infusion. Thrombolysis refers to the active administration of a thrombolytic agent (in this case, tPA). Catheter-directed thrombolysis involves the distribution of tPA through a multi-side hole infusion catheter to allow systemic distribution of the agent at a controlled rate over a length of time. Therefore, a patient who undergoes on-table thrombolysis prior or after the initiation of CDT receives tPA. On-table tPA is a bolus dose that is made into the area of thrombus and then followed by other various intervention. The patients in this review did not undergo post-procedural CDT.