Variables evaluated
Data collected included patient demographics, risk factors for DVT
development, characteristics of the thrombus, anticoagulation used, and
interventional therapies utilized. Risk factors for DVT included
inherited and acquired thrombophilias (prothrombin G20210A and Factor V
Leiden mutations, decreased protein C, S, and antithrombin, elevated
lipoprotein [a], homocysteine, and antiphospholipid antibodies),
hospital-related (presence or history of central venous catheters,
recent immobilization, surgery, or trauma), disease-related (infection,
cancer, inflammatory bowel disease, or nephrotic syndrome), or
medication-related (estrogen, steroids, or asparaginase).
Characteristics of the thrombus included laterality, veins involved,
extent of thrombus, and presence of pulmonary embolus (PE).
Interventional therapies included use of CDT, Angiojet for thrombectomy
and pharmacomechanical thrombectomy, Indigo system for mechanical
thrombectomy, stent placement, intravenous ultrasound [IVUS], and
percutaneous transluminal angioplasty [PTA].