Treatment characteristics
All patients in the cohort received anticoagulation, see Table
2 for details. In the “on-table” bolus group (n=7), the median tPA
dose was 7 mg (range 2-10 mg), and median tPA dose/kg was 0.2 mg/kg
(range 0.2-0.3 mg/kg). The median dose/kg/hr of tPA received in the
indwelling catheter group was 0.02 mg, with a range of 0.01-0.045 mg.
The number of days that tPA was infused in the catheter-directed group
was 1 in 59.1% (n=13), 2 in 13.6% (n=3), 3 in 18.2% (n=4), and 4 days
in 9.1% (n=2). See Table 2 for types of pharmacomechanical
devices used.