CL: clearance; F: bioavailability; i.d.: intradermal; k_a: absorption rate constant; RSE: relative standard error; s.c.: subcutaneous.

^A centered around 23 years. ^Bcentered around 70 kg.

Table 4 Characterization of adalimumab after passage through a glass vial, a syringe, or a syringe with a hollow microneedle (Syr. + MN), at 0 hours (0h) and after storage at 4°C for 4 hours (4h). Representative data of two independent experiments.