Figure 1 Periodic distribution of NIRS data from CR, CL, T5 and
T10 regions
ACP: Antegrade cerebral perfusion; CPB: Cardiopulmonary bypass
When compared to the baseline NIRS levels, more than 20% reduction was
observed in 17 patients’ T5 NIRS values (56,7%, p<0.001), and
22 patients’ T10 values (73.3%, p<0.001) during ASCP period
which was statistically more than the number of such patients in the
preceding periods. The patient with paraparesis was in this group. A
drop more than 36% of baseline occurred less frequently during the same
period (in 1 patient’s T5 and in 7 patients’ T10 NIRS values, p=1,00 and
p=0,016 respectively) with none of the patients experiencing any
neurologic event. The only patient with more than 36% reduction in both
T5 and T10 NIRS values had only 17 minutes of ASCP without any
postoperative neurologic complication.
s100β levels at the postoperative 6th hour fell
significantly with respect to the period corresponding to the end of
ASCP (2.086 ± 0.971 vs 1.082 ± 0.82; p<0.001) (Table 2).
Lactate levels increased with the onset of ASCP reaching its highest
level with termination of ASCP and diminishing afterwards in the
postoperative period (pΣ <0.001, Table 2,
Figure 2). Statistically significant differences were observed in
lactate levels between the pairs as before ASCP and during ASCP
(pΩ =0.002), during ASCP and at the end of ASCP
(pΨ<0.001) (Table 2). Lactate levels in
blood samples obtained from descending aorta during ASCP was
significantly higher than the samples drawn concurrently from radial
artery with a moderately positive correlation between them (4.52 ± 1.56
vs 3.86 ± 1.61 respectively, p=0.002 and r=0.655, p<0.001).