Legend: CAD, coronary artery disease; PAD, peripheral artery disease; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; PPI, permanent pacemaker implantation; EF, ejection fraction; PG, pressure gradient; AVB, atrioventricular block; IV cond, intraventricular conduction; RBBB, right bundle branch block; LBBB, left bundle branch block; FACT, Free State aortic valve calcium computed tomography; LVOT, left ventricular outflow tract; Asym cuspid calcif, asymmetric cuspid calcification; RCC, right coronary cusp; LCC, left coronary cusp; NCC, non-coronary cusp; SE, self expandable; BE, balloon expandable; Hgb, hemoblogin; CRP, C reactive protein; NLR, neutrophils to lymphocytes ratio.