Introduction:
DiGeorge syndrome is a primary immunodeficiency resulting from a
microdeletion 22q11.2 and leads to a multifaceted disorder. This
microdeletion results in abnormal development of third and fourth
pharyngeal pouches. The presentation and clinical features vary from
person to person and commonly include facial abnormalities,
hypoparathyroidism, heart defects, thymic hypoplasia, immunodeficiency,
and other clinical problems [1]. It is occasionally associated with
cytopenias, including idiopathic thrombocytopenic purpura (ITP) and
autoimmune hemolytic anemia (AIHA.) Usually, more than one cell line is
affected by the patient experiencing cytopenias. We report a case of
AIHA secondary to DiGeorge syndrome in an adult female, likely
precipitated by a viral illness and vitamin B12 deficiency.
Keywords: DiGeorge Syndrome, Autoimmune hemolysis, AIHA, B12
deficiency, Viral illness.