Sex |
Female |
Male |
Male |
Female |
Male |
Male |
Male |
Age of onset (months) |
7 |
9 |
9 |
6 |
7 |
6 |
7 |
Age at first visit (months) |
9 |
13 |
17 |
16 |
17 |
11 |
8 |
Fulfilled diagnostic criteria based on history |
− |
+ |
+ |
+ |
+ |
+ |
+ |
Fulfilled diagnostic criteria based on OFC |
+ |
− |
− |
− |
− |
− |
− |
History of symptoms owing to wheat consumption |
|
|
|
|
|
|
|
Vomiting 2–4 hours after eating a food containing wheat |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
Two or more episodes of repetitive vomiting after eating the same food |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
Episodes of repetitive vomiting 1–4 hours after eating 2 or more
different foods |
+ |
+ |
− |
+ |
+ |
+ |
+ |
Number of vomiting episodes before first visit |
6 |
4 |
3 |
4 |
4 |
2 |
3 |
Extreme lethargy with a suspected reaction |
− |
− |
− |
− |
− |
− |
+ |
Marked pallor with any suspected reaction |
− |
− |
+ |
− |
+ |
+ |
− |
Visit to emergency department due to a suspected reaction |
− |
− |
− |
− |
− |
+ |
− |
Requirement of intravenous fluid due to a suspected reaction |
− |
− |
− |
− |
− |
+ |
− |
Diarrhea (within 24 hours) |
− |
+ |
+ |
+ |
+ |
+ |
+ |
Hypotension |
− |
− |
− |
− |
− |
+ |
− |
Hypothermia |
− |
− |
− |
− |
− |
− |
− |
IgE-mediated skin and/or respiratory symptoms |
− |
− |
− |
− |
− |
− |
− |
Total IgE (IU/mL) |
13.2 |
11.1 |
<5.0 |
19.2 |
7.1 |
129 |
12.2 |
Wheat-sIgE (kUA/L) |
<0.35 |
<0.35 |
<0.35 |
0.42 |
<0.35 |
<0.35 |
<0.35 |
ω-5-gliadin sIgE (kUA/L) |
<0.35 |
<0.35 |
<0.35 |
<0.35 |
<0.35 |
<0.35 |
<0.35 |
Current complications |
|
|
|
|
|
|
|
Atopic dermatitis |
− |
+ |
+ |
− |
− |
− |
− |
Recurrent wheezing |
− |
− |
− |
− |
− |
− |
− |
IgE-mediated food allergy
|
−
|
−
|
−
|
−
|
−
|
+
(egg)
|
−
|
FPIES (other than wheat)
|
+
(fish)
|
−
|
−
|
−
|
+
(barley)
|
−
|
−
|
Age at last reaction to wheat (months) |
28 |
14 |
10 |
18 |
19 |
45 |
8 |
Age at which tolerance was confirmed (months) |
44 |
34 |
42 |
48 |
47 |
NA |
13 |