Case report
A 75-year-old female presented with a three-month history of pruritic
purulent and crusted lesions over the scalp. She had been treated with
multiple oral antibiotics and a topical cream consisting of clobetasol
and salicylic acid for one month without any improvement. The patient
had no medical history other than hypertension. She was in a good
general condition and had not received any immunosuppressant drug. There
was not any similar disease in other family members. Physical
examination showed multiple erythemato-edemathous papules and plaques
with yellow crust, pustule formation, and hair loss involving the vertex
and occipital area of the scalp (Fig 1). There were no other lesions in
any other parts of the skin, nails and mucosa. Values of serum blood
chemistry were in the normal range. The patient’s immune profile was
normal. The direct exam with 20% KOH showed an endothrix infection and
the mycological culture showed the growth of Trichophyton
Violaceum . Bacterial culture was negative. Skin biopsy of the scalp
lesions showed an acute superficial and deep folliculitis with
intrafollicular mycelial fungal infection consistent with tinea capitis
(endothrix), on hematoxylin and eosin staining (Fig 2A & 2B).
PAS-stained slides showed endothrix septate hyphae invading the hair
shafts (Fig 2C). Fluorescent microscopy showed endothrix infection by
green fluorescent, septate hyphae and spores (Fig 2D). The patient was
treated with prednisolone 15mg daily for one month and oral itraconazole
400 mg daily, which was gradually tapered to 100 mg daily at the last
two months. Also, the patient and all family members were treated with
2.5% selenium sulfide shampoo. There was complete clearance of the
lesions and acceptable hair regrowth (Fig 3).