Conclusion
Our findings suggest that the ADRB2 gene Arg16Gly polymorphism may be a reliable predictor of the response to salbutamol in asthmatic patients. While, we found no valid evidence to support the effect of the Gln27Glu polymorphism on salbutamol responsiveness. These findings could contribute to the development of individualized treatment and improve the effectiveness of the management of asthma. However, we have to acknowledge the limited power of our study. Therefore, we call for more well-designed studies with larger sample size to accurately verify the relationship among ADRB2 polymorphisms and salbutamol response in asthmatic patients.
Conflict of interest: The authors declare that they have no known competing financial interests or personal relationships.