Conclusion
Our findings suggest that the ADRB2 gene Arg16Gly polymorphism
may be a reliable predictor of the response to salbutamol in asthmatic
patients. While, we found no valid evidence to support the effect of the
Gln27Glu polymorphism on salbutamol responsiveness. These findings could
contribute to the development of individualized treatment and improve
the effectiveness of the management of asthma. However, we have to
acknowledge the limited power of our study. Therefore, we call for more
well-designed studies with larger sample size to accurately verify the
relationship among ADRB2 polymorphisms and salbutamol response in
asthmatic patients.
Conflict of interest: The authors declare that they have no
known competing financial interests or personal relationships.