Figure legends
Figure 1. Inter- and intraindividual variability of serum
concentrations and daily dose of atomoxetine in various CYP2D6/2C19
genotype subgroups. A and B: The effect of
CYP2D6 genotype subgroups not
carrying (N ) or carrying the CYP2C19*2 allele variant
(*2 ) on serum concentration (A) and daily dose (B) of
atomoxetine. This effect was analysed using linear mixed model without
covariates with CYP2D6 NM not carrying CYP2C19*2 allele variant
as reference group. *P-values <0.05, and the p-values are
Sidak-adjusted. The various CYP2D6 genotype subgroups are
represented with red dots for poor metabolizers (PM), yellow dots for
intermediate metabolizers (IM), green dots for normal metabolizers (NM)
and blue dots for ultra-rapid metabolizers (UM), respectively.