References
1. van Haren FMP, Page C, Laffey JG, Artigas A, Camprubi-Rimblas M,
Nunes Q, Smith R, Shute J, Carroll M, Tree J, Carroll M, Singh D,
Wilkinson T, Dixon B. Nebulised heparin as a treatment for COVID-19:
scientific rationale and a call for randomised evidence. Crit Care 2020;
24: 454.
2. Tree JA, Turnbull JE, Buttigieg KR, Elmore MJ, Coombes N, Hogwood J,
Mycroft-West CJ, Lima MA, Skidmore MA, Karlsson R, Chen YH, Zhang Y,
Spalluto CM, Staples KJ, Yates EA, Gray E, Singh D, Wilkinson T, Page
CP, Carroll MW. Unfractionated heparin inhibits live wild-type
SARS-CoV-2 cell infectivity at therapeutically relevant concentrations.
Br J Pharmacol 2020.
3. Dixon B, Smith R, Campbell D, Moran J, Doig G, Rechnitzer T, MacIsaac
C, Simpson N, van Haren F, Ghosh A, Gupta S, Broadfield E, Crozier T,
French C, Santamaria J. Nebulised heparin for patients with or at risk
of acute respiratory distress syndrome: a multicentre, randomised,
double-blind, placebo-controlled phase 3 trial. Lancet Respir Med
[accepted for publication 05 October 2020; in-press].
4. Kahan BC, Forbes G, Cro S. How to design a pre-specified statistical
analysis approach to limit p-hacking in clinical trials: the Pre-SPEC
framework. BMC Med 2020; 18: 253.
5. Gamble C, Krishan A, Stocken D, Lewis S, Juszczak E, Dore C,
Williamson PR, Altman DG, Montgomery A, Lim P, Berlin J, Senn S, Day S,
Barbachano Y, Loder E. Guidelines for the Content of Statistical
Analysis Plans in Clinical Trials. JAMA 2017; 318: 2337-43.
6. Petkova E, Antman EM, Troxel AB. Pooling Data From Individual
Clinical Trials in the COVID-19 Era. JAMA 2020.
7. Li J, Pavlov I, Laffey JG, Roca O, Mirza S, Perez Y, McNicholas B,
Cosgrave D, Vines D, Tavernier E, Ehrmann S. Meta-trial of awake prone
positioning with nasal high flow therapy: Invitation to join a pandemic
collaborative research effort. J Crit Care 2020; 60: 140-42.
8. Fergusson D, Aaron SD, Guyatt G, Hebert P. Post-randomisation
exclusions: the intention to treat principle and excluding patients from
analysis. BMJ 2002; 325: 652-4.
9. Pedroza C, Tyson JE, Das A, Laptook A, Bell EF, Shankaran S, for the
Eunice Kennedy Shriver National Institute of Child H, Human Development
Neonatal Research N. Advantages of Bayesian monitoring methods in
deciding whether and when to stop a clinical trial: an example of a
neonatal cooling trial. Trials 2016; 17: 335.
10. Saville BR, Connor JT, Ayers GD, Alvarez J. The utility of Bayesian
predictive probabilities for interim monitoring of clinical trials. Clin
Trials 2014; 11: 485-93.
11. Schulz KF, Altman DG, Moher D, Group C. CONSORT 2010 statement:
updated guidelines for reporting parallel group randomised trials. BMJ
2010; 340: c332.
12. Stone JH, Frigault MJ, Serling-Boyd NJ, Fernandes AD, Harvey L,
Foulkes AS, Horick NK, Healy BC, Shah R, Bensaci AM, Woolley AE,
Nikiforow S, Lin N, Sagar M, Schrager H, Huckins DS, Axelrod M, Pincus
MD, Fleisher J, Sacks CA, Dougan M, North CM, Halvorsen YD, Thurber TK,
Dagher Z, Scherer A, Wallwork RS, Kim AY, Schoenfeld S, Sen P, Neilan
TG, Perugino CA, Unizony SH, Collier DS, Matza MA, Yinh JM, Bowman KA,
Meyerowitz E, Zafar A, Drobni ZD, Bolster MB, Kohler M, D’Silva KM, Dau
J, Lockwood MM, Cubbison C, Weber BN, Mansour MK, Investigators BBTT.
Efficacy of Tocilizumab in Patients Hospitalized with Covid-19. N Engl J
Med 2020.