CONCLUSION
Laryngeal function failure following (C)RT affects a considerable
proportion of patients and smokers appear to be at a significantly
increased risk. Large-scale multi-centre studies will likely be required
to more accurately identify risk factors, and aid in development of an
NFL risk prediction tool. The addition of quantitative data including
molecular subclassification and radiomics to enrich this dataset may
provide significant predictive and prognostic input into future clinical
decision-making.