CONCLUSION
Laryngeal function failure following (C)RT affects a considerable proportion of patients and smokers appear to be at a significantly increased risk. Large-scale multi-centre studies will likely be required to more accurately identify risk factors, and aid in development of an NFL risk prediction tool. The addition of quantitative data including molecular subclassification and radiomics to enrich this dataset may provide significant predictive and prognostic input into future clinical decision-making.