SIGNIFICANT STATEMENTS
In this original research paper, I write the Schrödinger equation in quantum reference frames. As a part of this project that the quantum canonical transformations are defined outside of the Hilbert space, we finally designed small molecules the RoccuffirnaTM’s chemical structures that comprising the highest binding free energy docking values based on reliable comparisons of numerical cryptographical models with observed docking data by using Galilean Black Hole Transformations, Quantum chemistry phenomena, and Pharmacophoric Merging Hyper-algorithms. ( 31, 32, 37-43 As a by-product of the fact that the quantum canonical transformations are defined outside of the Hilbert space, I was able of the QMMM construction of the Roccuffirna small molecule by introducing numerical cosmological calculations to investigate different quantum chemistry phenomena.