Exclusion criteria
Studies fulfilling the following criteria will be excluded:
- Conference abstracts
- Narrative reviews, editorials and correspondence
- Systematic reviews (reference lists will first be scanned for relevant
original articles)
- Qualitative studies
- Case reports and case series
- Animal studies
- Studies in which allergies are defined based on sensitization tests
alone without a history following ingestion.
- Studies may be excluded based on risk of bias and applicability
Each study will be screened by two reviewers independently based on the
title and abstract according to the inclusion and exclusion criteria
(described below). If there are any discrepancies between the reviewers,
a third reviewer will adjudicate. When the studies have been selected,
the full texts will be reviewed to confirm they meet the inclusion
criteria. Data will be extracted from these studies and the quality will
be assessed for risk of bias and applicability. Studies which satisfy
the inclusion criteria but are not in English will be translated prior
to data extraction and quality assessment.