The distribution of IKZF1 Δ2-8/ALB gene deletion levels
The distribution of IKZF1 deletion levels is shown in Table 2. The level
of IKZF1 deletions in the 74 patients was ranged 0.01% to 243.76%.
There were 45 patients (60.8%) who had IKZF1Δ2-8/ALB deletions of <
1%, including only a single patient (2.2%) who was BCR-ABL1 fusion
gene positive, while the others were negative. Of the 29 patients with
IKZF1Δ2-8/ALB deletions of ≥ 1%, nine patients (31.0%) were BCR-ABL1
fusion gene-positive. Patients with IKZF1Δ2-8/ALB deletions of ≥ 1% had
a higher BCR-ABL1 positive rate than those with IKZF1Δ2-8/ALB deletions
of < 1% (31.0% vs. 2.2%, P =0.001), as shown in Figure 1.