Simulation Variable |
|
|
Initial number of beads |
0 |
|
Grid Number |
2500 |
|
Grid dimension |
10 Micron |
|
Confluence |
Half of total grid (1250) |
|
Number of control-steps |
20, 50, 400 (variable) |
Assumed |
Control Time interval
|
8-hour,
3.2-hour ,
24 minutes
|
|
Number of beads that can
be added at each control step
|
10
|
|
Initial number of naïve
cells to begin with in control area
|
20
|
Assumed
|
Total time |
160 hours (weeklong growth) |
|
Cell Variable |
|
|
Mean value of
Regeneration Age
|
2 days
|
Assumed
|
Maximum age at which
a cell can regenerate
|
3.5 days
|
Assumed
|
Probability of conversion |
45, 90
(\(\ \frac{\text{Conversion}}{100\ \times\ Collisions}\ \)) |
Assumed |
Exhaustion Rate |
1,4 (\(\frac{\text{Unit\ potency}}{100\ collision}\)) |
Assumed |
Natural Exhaustion |
1, 10
(\(\ \frac{\text{Unit\ potency}}{\ 100\ \times\ timesteps\ }\ \)) |
Assumed |
Regeneration Rate |
1, 5
(\(\frac{\text{Regeneration}}{100\ \times\ timesteps}\)) |
Assumed |
Asymmetric regeneration |
True/False |
Assumed |
Potency value above which a
cell is considered robust
|
0.8
|
Assumed
|
Potency value below which a cell is
considered exhausted
|
0.2
|
Assumed
|