Other rare types of clinical presentation
Another rare presentation of MOGAD is found in children that show
similar symptoms of ADEM, however, with a more progressive disease
course (61). Here clinical course and symmetrical confluent cerebral MRI
changes resemble that of children with leukodystrophy, hence the term
leukodystrophy-like phenotype. Recently, overlapping central and
peripheral nervous system syndromes have been described as potential
additional MOGAD phenotypes, including cranial nerve involvement,
myeloradiculitis, inflammatory neuropathies and combined central and
peripheral demyelination syndromes (62–66).