Encephalitis
Epileptic seizures were repeatedly described in a subgroup of MOGAD
patients and are more common than in AQP4-IgG seropositive NMOSD
(55–57), occurring in around 20% of all adult and paediatric MOGAD
patients (58).
Encephalitis with and without seizures is now becoming increasingly
recognised as an important clinical phenotype of MOGAD (58). Here,
patients can show neuropsychiatric symptoms, behavioural changes,
seizures, and memory or speech problems (59). Recently, encephalitis
with MOG-IgG has been described as the most common type of autoimmune
encephalitis in children (60).