Surgical procedure type and interventions
Plasma lidocaine levels did not statistically differ between diagnostic and therapeutic surgical groups at any measured time point. All p-values were calculated as >0.05 utilising Mann-Whitney U-tests.
Peak lidocaine plasma levels were also analysed by surgical procedure group, diagnostic or therapeutic, and the use of adrenaline, endotracheal (ET) suction, both or neither. Due to the very small numbers in some subgroups, comparison tests are not robust. However, the plot suggests that there is no difference in the distribution of peak lidocaine plasma between these groups.
This suggests surgical suction and application of vasoconstrictors have no effect on peak plasma lidocaine levels.