Dose
Dosing regimes did vary between practitioners dependent upon usual practice. Dosing regimes in the study comprised of 5.0 (4.93,5.0)[3.0,5.0] mg/kg, median (IQR)[range]. P-values from Mann-Whitney U test demonstrate no significant difference between the distribution of peak lidocaine plasma levels between doses at 5mg/kg and <5mg/kg (p=0.18). However, a narrow IQR within toxic limits has been suggested with doses <5mg/kg. This could imply a safer dosing profile, with no clinical adverse effects demonstrated for both the patient and surgical conditions.
Secondary outcomes