Five Key Points
- Strong linear correlation exists between weight and age for our cohort
(r=0.88)
- A significant relationship exists between higher peak plasma levels
and ages ≤18 months (p=0.00973)
- Data suggests a potential relationship of lower weights achieving
higher peak plasma levels (p=0.0516)
- Higher peak plasma lidocaine levels occur with total dose volumes
between 2 and 3mls of 2% lidocaine local anaesthetic (p=0.03)
compared with <2ml total dose volumes
- Reduced IQR variation of peak plasma lidocaine levels exists when
lidocaine dosing is <5mg/kg.
Key words
Airway endoscopy, drug
levels, Lidocaine, paediatric airway, paediatric anaesthesia,
topical anaesthesia, toxicity