Results
Study demographics and baseline
Table 1 summarises the study demographics, baseline and descriptive
data.
We found strong linear correlation between weight and age (r=0.88) as
demonstrated in Figure 1. This adds strength to our study results in an
era of paediatric obesity and the potential confounding effects of
weight and age on drug handling.
Primary outcome – Peak plasma lidocaine levels after airway
topicalisation
Linear regression models were used to assess the relationship between
peak lidocaine plasma concentration and variables of age, weight, volume
and dose. The correlation coefficient (r) and p-values are derived from
Spearman’s correlation test.