Results
Study demographics and baseline
Table 1 summarises the study demographics, baseline and descriptive data.
We found strong linear correlation between weight and age (r=0.88) as demonstrated in Figure 1. This adds strength to our study results in an era of paediatric obesity and the potential confounding effects of weight and age on drug handling.
Primary outcome – Peak plasma lidocaine levels after airway topicalisation
Linear regression models were used to assess the relationship between peak lidocaine plasma concentration and variables of age, weight, volume and dose. The correlation coefficient (r) and p-values are derived from Spearman’s correlation test.