What’s already known about this topic?
VEGF (Vascular endothelial growth factor), PDGF (Platelet derivated growth factor), which are studied in many cancer types, are already known prognostic angiogenic factors, while thrombospondin is a prognostic antiangiogenic factor. Diffuse large B cell Lymphoma (DLBCL) has a poor prognosis in patients who do not respond to the first treatment despite many treatment options. Angiogenic and anti-angiogenic factors are important prognostic factors for DLBCL.