Abbreviations
ZMTM: Zhuang Medicated Threads; PPS: Perimenopausal Syndrome; E:
Estradiaol; IL-2: Interleukin 2.
Ethics approval and consent to participate: All animal
experiments were authorized by the Guangxi Zhuang Yao Medicine Center of
Engineering and Technology, Guangxi University of Chinese Medicine and
Hubei Minzu University Animal Ethics Committee and carried out in
compliance with the institutional guidelines.
Consent to publish : Not Applicable
Availability of data and materials : The datasets used and/or
analyzed during the current study are available from the corresponding
author on reasonable request.
Competing interests : The authors declare that they have no
competing interests
Funding : This work was sponsored by the National Natural
Science Foundation of China (No.81660830)
;Guangxi Program on Science and Technology Project: Gui Ke AD1924518;
Development Program of High-level Talent Team under Qihuang Project of
Guangxi University of Chinese Medicine(No.2018005);Guangxi first
class discipline construction project (No. Gui Jiao Ke Yan [2018]12).
The funders had no role in study design, data collection and analysis,
decision to publish, or preparation of manuscript.
Authors’ Contributions : K.L. is mainly responsible for the
design and operation of the whole experiment. Y.Z., Z.C., and J.C.
primarily assisted in the process of the investigation. Z.H. and Y.P.
wrote and revised the manuscript. DL and G.F. provided the overall idea
for the experiment and revised the paper in the later stage. All authors
have read and approved the manuscript before submission.
Acknowledgements : Not Applicable