Causes of death in patients with and without aGVHD grade III/IV
At a mean follow-up, for alive patients, of 38.9 months (±SD 25.8
months) 15/166 (9%) and 8/17 (47%) of patients without and with aGVHD
grade III/IV were deceased, respectively. The causes of death in
patients without and with aGVHD grade III/IV included recurrent disease
(13.3% vs 12.5%), organ failure (40% vs 25%), bacterial infection
(33% vs 25%), fungal infection (0 vs 12.5%) GVHD (0% vs 25%),
2nd malignancy (6.7% vs 0%), and unknown (6.7% vs
0%).