Study Limitations
There are several limitations to this study. One of the limitations is
the lack of measuring TrxR enzyme activities. Another limitation is that
thiol-containing compounds that contribute to plasma dynamic thiol
balance have not been examined separately. Further studies showing the
thiol balance in all stages of CKD patients, with a larger population
size, will contribute to understanding the role of thiol balance and
TrxR enzyme in the pathogenesis of the disease.