Abstract:
Objective Papillary cystadenoma is a epithelial benign tumor of
the salivary gland, most commonly in the oral cavity, head and neck.
There was no difference in the sex distribution of patients, and the age
of onset was 30-50 years old. The clinical manifestations are: slow
growth local mass, long course of disease, some can be as long as
decades, most patients have no obvious conscious symptoms, a few
patients can appear local pain or distension. However, papillary
cystadenoma of the esophagus is very rare, and few cases have been
reported.
Methods We report a case of papillary cystadenoma of the lower
esophagus and its treatment by endoscopy. The patient had no obvious
complaint of discomfort. Routine gastroscopy found submucosal
protuberant lesions in the lower segment of the esophagus (Figure 1),
and endoscopic ultrasonography suggested cystic and solid lesions
originating from the muscular layer of the esophageal mucosa, thus
mesenchymal tumor was preliminarily diagnosed (Figure 2). After the
exclusion of relevant contraindications, preoperative examinations were
completed and the tumor was completely removed by esophageal submucosal
tumor excision under endoscopy (Figure 3). Postoperative pathology
indicated the tumor is papillary cystadenoma, and immunohistochemistry
indicated that: CK7(+), CK(+), and basal cells of P63 (+) (Figure 4-6).
Results Due to the rare case, combined with the process of the
diagnosis and treatment of this case, we reviewed the relevant reports
on the papillary cystadenoma of the digestive tract in the past 60
years, in order to help clinicians to improve their understanding and
treatments of the papillary cystadenoma.
keywords: Endoscopic submucosal mass excision、papillary
cystadenoma of the esophagus