Conclusions:
The mechanism by which the virus gains access to the CNS and why
patients with AD are at higher risk of virus infection are not well
understood.. Although people infected with SARS-CoV-2 frequently display
neurological symptoms, multiple manifestations remain unrecognized.
First, neurological symptoms are often ignored because the first goal is
to combat respiratory symptoms. In addition, clarifying the mechanisms
by which SARS-CoV-2 invades and spreads throughout the CNS is important
for preventing and ameliorating neurological symptoms. Studies are
imperatively needed to clarify the potential mechanisms underlying the
elevated susceptibility and mortality rate of AD patients to COVID-19
and discover preventive strategies to minimize the risk of viral
infection among patients with AD.