FIGURE 1 Schematic of the microreactor system used to determine the kinetics of CB nitration
It is worth noting that due to the limited solubility of CB in sulfuric acid, the mass ratio of sulfuric acid to nitric acid in solution 2 was kept at approximately 240 to meet the molar ratio of nitric acid to CB. The large amount of sulfuric acid as a solvent can absorb the reaction heat. In addition, the reaction conversion was controlled at a low level, and the thermostat was used to continuously remove the reaction heat. The calculated increase in the reaction temperature was less than 0.3 °C, which can be completely negligible. The calculation process is provided in the Supporting Information. It can be considered that the reaction proceeded under isothermal conditions. Each experiment was repeated three times. The error bars are marked in figures, and the final results are the average values of the three measurements.