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\begin{document}

\title{\textbf{Office-based Transnasal Oesophagoscopy: evaluating the safety,
efficacy and application in head and neck cancer patients}}



\author[1]{Ravneet Grewal}%
\author[2]{Narun Tantichirasakul}%
\author[3]{Benjamin Miller}%
\author[4]{Natalie Watson}%
\author[5]{Yakubu Karagama}%
\affil[1]{King's College London GKT School of Medical Education}%
\affil[2]{Guy's King's College and Saint Thomas' Hospitals' Medical and Dental School of King's College London}%
\affil[3]{Guy's and St Thomas' NHS Foundation Trust ENT H\&N}%
\affil[4]{Guy's Hospital}%
\affil[5]{Guy's and St Thomas' NHS Foundation Trust}%


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  \date{June 16, 2024}


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\begin{abstract}
Key Points * Transnasal Oesophagoscopy (TNO) is an approach to inspect
the upper aerodigestive tract, especially in the head and neck cancer
(HNCA) population that present with dysphagia. * Twenty-five (25)
office-based TNO procedures were performed, with a same-day discharge
rate of 96\% (24/25) and no reported complications. * This case series
is the first to compare preoperative and postoperative outcomes (EAT-10)
following stricture dilatation using TNO in the UK. Our results show a
statistically significant improvement in symptom severity (EAT-10
scores) (n=11, P=0.001). In the majority of these patients, strictures
were due to post-radiation complications. Biopsy in 4/5 cases was
sufficient for diagnosis/ruling out disease. Of these patients, 80\% had
a previous HNCA. * This study identifies the remit for a new `one-stop'
TNO service for suspected cancer referrals, of which a large proportion
are patients with a previous HNCA. Surveillance, therapeutics and
diagnostics can be achieved in a single visit. * Earlier staging or
treatment may be achieved due to a fast turnover in clinic%
\end{abstract}%



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