Baseline characteristics:
Baseline characteristics are provided in Table 1 . Treatment was
instituted as per chemotherapy protocols of the intitute at that period
of time which were differed among patients. Details of relevant
cumulative drugs are provided. Radiotherapy was received by all patients
as per protocol(1260cGy for prophylaxis and 1800cGy to treat CNS
positive leukemia). As per treatment protocol at the time, our cohort
received either Protocol A or B. Protocol B included high dose
methothrexate, triple IT and a higher dose of dexamethasone and
cyatarabine as compared to protocol A. Our cohort averaged a total of
27.1 months of delay in schooling.