Baseline characteristics:
Baseline characteristics are provided in Table 1 . Treatment was instituted as per chemotherapy protocols of the intitute at that period of time which were differed among patients. Details of relevant cumulative drugs are provided. Radiotherapy was received by all patients as per protocol(1260cGy for prophylaxis and 1800cGy to treat CNS positive leukemia). As per treatment protocol at the time, our cohort received either Protocol A or B. Protocol B included high dose methothrexate, triple IT and a higher dose of dexamethasone and cyatarabine as compared to protocol A. Our cohort averaged a total of 27.1 months of delay in schooling.