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\begin{document}

\title{Do carboxyhemoglobin and methemoglobin levels predict the return of
spontaneous circulation and prognosis of cardiac arrest patients?}



\author[1]{Onur Tezel}%
\author[1]{Sedat Bilge}%
\author[1]{Yahya Ayhan Acar}%
\author[1]{Gokhan Ozkan}%
\affil[1]{Ankara Gülhane Eğitim ve Araştırma Hastanesi}%


\vspace{-1em}



  
  \date{June 17, 2024}


\begingroup
\let\center\flushleft
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\maketitle
\endgroup





\selectlanguage{english}
\begin{abstract}
Introduction: Early prediction of return of spontaneous circulation
(ROSC) for cardiac arrest (CA) patients is a major challenge. This
study's goal was to investigate the value of the carboxyhemoglobin
(COHb) and methemoglobin (MetHb) levels as a predictive marker for ROSC
and prognostic marker for patients who achieve ROSC. Methods: A total of
241 adult patients (109 female, 132 male) diagnosed as non-traumatic CA
were included in the study. The patients were divided into two groups
based on whether they achieved ROSC. Complete blood count parameters,
routine biochemistry measurements, coagulation parameters, and blood gas
analysis, and cardiac markers values were compared between the groups.
Results: COHb levels were significantly lower in the non-ROSC group
(0.71 \selectlanguage{ngerman}± 0.57\%) than in the ROSC group (0.95 ± 0.76\%) and in the
non-survival group (0.78 ± 0.53\%) compared to the survivor group (1.45
± 1.31\%) (p =0.002, 0.022 respectively). There was no significant
difference between the ROSC and non-ROSC groups and survivor group and
non-survivor groups in terms of MetHb levels (p = 0.769 and 0.668,
respectively). Conclusions: COHb levels in the blood gas analysis at the
time of admission could be used as a predictive marker for ROSC and
prognostic marker for the patients who achieved ROSC.%
\end{abstract}\selectlanguage{ngerman}%



\sloppy


\textbf{Do carboxyhemoglobin and methemoglobin levels predict the return
of spontaneous circulation and prognosis of cardiac arrest patients?}

\textbf{Abstract}

\textbf{Introduction:} Early prediction of return of spontaneous
circulation (ROSC) for cardiac arrest (CA) patients is a major
challenge. This study's goal was to investigate the value of the
carboxyhemoglobin (COHb) and methemoglobin (MetHb) levels as a
predictive marker for ROSC and prognostic marker for patients who
achieve ROSC.

\textbf{Methods:} A total of 241 adult patients (109 female, 132 male)
diagnosed as non-traumatic CA were included in the study. The patients
were divided into two groups based on whether they achieved ROSC.
Complete blood count parameters, routine biochemistry measurements,
coagulation parameters, and blood gas analysis, and cardiac markers
values were compared between the groups.

\textbf{Results:} COHb levels were significantly lower in the non-ROSC
group (0.71 \selectlanguage{ngerman}± 0.57\%) than in the ROSC group (0.95 ± 0.76\%) and in the
non-survival group (0.78 ± 0.53\%) compared to the survivor group (1.45
± 1.31\%) (p =0.002, 0.022 respectively). There was no significant
difference between the ROSC and non-ROSC groups and survivor group and
non-survivor groups in terms of MetHb levels (p = 0.769 and 0.668,
respectively).

\textbf{Conclusions:} COHb levels in the blood gas analysis at the time
of admission could be used as a predictive marker for ROSC and
prognostic marker for the patients who achieved ROSC.

\textbf{Keywords:} Carboxyhemoglobin, cardiac arrest, methemoglobin,
ROSC, prognosis

\textbf{What is already known about this topic?}

The significance of the COHb and MetHb levels for the prognosis of
cardiac arrest patients is unknown.

\textbf{What does this article add?}

COHb levels could be used as a post-CPR prognostic marker for cardiac
arrest patients.

\textbf{Introduction}

The prognosis of cardiac arrest (CA) remains poor, despite the advances
in treatment in recent years (1). The primary goal of cardiopulmonary
resuscitation (CPR) is to achieve the return of spontaneous circulation
(ROSC). Deciding when to stop CPR and not knowing how long the CPR will
take and how it will end are the main problems for rescuers. Biomarkers,
such as Interleukin-6, High sensitive C reactive protein, and S-100 B
protein, have been studied as an early marker of post-CPR prognosis and
predictors for ROSC (2,3). However, these biomarkers are not routinely
performed in the emergency department, add cost, and incur a time delay.
These delays diminish their value for CA patients. Studies of routinely
available laboratory markers have shown that high blood sugar, low
potassium, high platelet count, and elevated lactate levels are
associated with poor prognosis in patients with CA. Nevertheless, a
consensus has not been achieved on a standardized biomarker in this
regard (4--7). For healthcare professionals, blood gas analysis with
rapid results is an important tool in terms of diagnosis and treatment
of reversible causes of CA (hypoxia, hyperpotassemia, hypopotassemia,
hypovolemia, and acidosis). Carboxyhemoglobin (COHb) and methemoglobin
(MetHb) levels can be easily measured by blood gas analysis and do not
require additional costs.

COHb and MetHb are variants of normal hemoglobin. Both molecules are
formed from hemoglobin as a result of different biochemical processes
(8). COHb is formed by the binding of carbon monoxide (CO), which is
formed endogenously by hemoglobin metabolism or exogenously inhaled (8).
It has been reported that CO is involved in various functions, such as
vasodilation, angiogenesis, vascular remodeling, and inflammatory
response (8,9). The reported blood COHb level is approximately 1.0\% in
non-smokers and 5.5\% in patients with a smoking history (10). In some
studies, it has been reported that high and low COHb levels are
associated with poor clinical prognosis in various pathological
conditions, including pulmonary embolism (PTE), acute ischemic heart
disease, and critically ill patients in intensive care units (ICU)
(11--13).

MetHb formation results from oxidative processes in which one or more of
the four iron atoms in the hemoglobin molecule are converted to a ferric
state and, thus, unable to bind oxygen. When naturally produced nitric
oxide (NO) interacts with hemoglobin endogenous MetHb is formed. Large
amounts of NO can be produced in various critical diseases, such as
sepsis or septic shock (14). Increased free NO levels in the circulation
can cause the formation of MetHb (15,16). In conclusion, it has been
reported that MetHb levels increase in patients with sepsis and PTE
(11,14). To our knowledge, no study has yet investigated the predictive
value of COHb and MetHb levels in CA cases.

This study aimed to investigate the role of the COHb and MetHb levels in
predicting the ROSC in patients with non-traumatic cardiac arrest who
underwent CPR and to determine the predictive value of the COHb and
MetHb levels in patients who achieve ROSC.

\textbf{Methods}

The study was approved by the Ethics Committee for the Non-Invasive
Research at the Gulhane Health Sciences University (Committee IRB
approval number: 2020/06-decision no: 2020/126).

Study design and patient selection

All non-traumatic cardiac arrest patients admitted to the emergency
department from November 1 2016 to January 31 2020 were screened in the
electronic patient management system (FONET®, Information Technology
Incorporation, Turkey). Patient charts were screened, as well as an
electronic patient management system. Patients who were younger than 18
years and who had missing information were excluded. All non-traumatic
CA patients without the exclusion criteria were included in the study
(Figure-1).

Age, gender, complete blood count (CBC) parameters of the patients,
routine biochemistry measurements, coagulation parameters, and blood gas
analysis, cardiac markers, whether ROSC was achieved or not, the initial
rhythm {[}Asystole, Ventricular Fibrillation (VF), Pulseless Ventricular
Tachycardia (VT), Pulseless Electrical Activity (PEA){]}, duration of
CPR (min), and hospital admission status were recorded. The patients
were divided into two groups as patients in whom ROSC was achieved (ROSC
group) or those in whom ROSC was not achieved (non-ROSC group). ROSC was
defined as spontaneous circulation and was achieved longer than 20 min.
The ROSC group was also divided into two subgroups as survivors
(discharged from the hospital) and non-survivors (mortality occurred
during hospital stay).

Power analysis

The sample size was calculated with an alpha value of 0.05, 80\% power,
an enrollment ratio of 1, and COHb values of 0.9 in group 1 (ROSC group)
and 0.54 in group 2 (no-ROSC group), yielding that 26 patients in either
group making a total of 52 participants would be included in the study
(17,18).

Laboratory analysis

By the protocol of the emergency service where the study was conducted,
blood samples are taken simultaneously for CBC, routine biochemistry,
blood gas analysis, cardiac markers, and coagulation parameters within
the first 4 mins of the onset of CPR.

CBC (Beckman Coulter Unicell DxH 800, CA 92821 USA), blood gas
parameters (Radiometer ABL800 FLEX, 2700 Bronshoj Denmark), routine
biochemistry (Beckman Coulter AU680, CA 92821 USA), cardiac Troponin
(cTn), creatine kinase MB isoenzymes (CKMB) (Beckman Coulter DxI 800
Access immunoassay systems, CA 92821 USA), PTZ-INR, and D-Dimer (Sysmex
CS-2500, Kobe 651-0073 Japan) were measured in the emergency
biochemistry laboratory.

Statistical analysis

The categorical variables were presented as frequency and percentages.
Continuous variables were presented as mean ± standard deviation. The
Kolmogorov Smirnov test was used for testing whether the variables were
distributed normally. Student's t-test was used for binary comparison of
continuous variables conforming to the normal distribution, Mann-Whitney
U test for non-compliant ones, and Chi-square test for comparison of
categorical data. A p-value of \textless{} 0.05 was considered
statistically significant. The statistical analysis software was SPSS
Statistics for Windows, version 22.0 (SPSS Statistics for Windows,
Version 22.0. IBM Corp., Armonk, N.Y., USA).

\textbf{Results}

A total of 241 patients (109 female, 132 male) were included in the
study. Of the patients (n = 241), 56.01\% (n = 135) were in the ROSC
group and 43.98\% (n = 106) were in the non-ROSC group. There were no
statistically significant differences in age and gender between the ROSC
and non-ROSC groups (Table I).

CPR duration was 14.12 ± 11.67 min in the ROSC group, while it was 48.26
± 10.61 min in the non-ROSC group, and the difference between them was
statistically significant (p \textless{} 0.001). In terms of the initial
arrest rhythm (Asystole, VF, VT, PEA); there was a statistically
significant difference between the ROSC group (n = 91, 8, 3, and 21,
respectively) and the non-ROSC group (n = 95, 0, 0, and 10,
respectively) (p = 0.003).

When comparing the ROSC group and the non-ROSC group in terms of routine
biochemistry and cardiac markers, the urea, creatinine, potassium, and
cTn levels in the non-ROSC group (125.91 ± 88.71 mg dL-1, 2.47 ± 1.73 mg
dL-1, 5.13 ± 1.33 mmol L-1, and 971.05 ± 2674.55 pg mL-1, respectively)
were higher than the ROSC group (88.6 ± 65.08 mg dL-1, 1.87 ± 1.32 mg
dL-1, 4.69 ± 1.29 mmol L-1, and 578.69 ± 1770.28 pg mL-1, respectively)
and the differences between them were statistically significant (p
\textless{} 0.001, 0.001, 0.014, and 0.005, respectively). There was no
statistically significant difference between these groups in terms of
other routine biochemistry and cardiac markers (Table II).

When comparing the ROSC group and the non-ROSC group in terms of blood
gas parameters, the COHb level in the non-ROSC group (0.71 ± 0.57\%) was
lower than the COHb level in the ROSC group (0.95 ± 0.76\%), and the
difference between them was statistically significant (p = 0.002) (Table
II). There was no statistically significant difference between these
groups in terms of other blood gas parameters.

Of the patients who achieved ROSC and could be followed up (n = 78),
82.05\% (n = 64) died (non-survivor group), and 17.95\% (n = 14) were
discharged from the hospital (survivor group). The mean age of the
non-survivor group was 71.98 ± 11.95 years, while the mean age of the
survivor group was 59.36 ± 20.96 years and the difference between them
was statistically significant (p = 0.025). In terms of gender, there was
no statistically significant difference between these groups (Table
III).

The CPR duration was 17.17 ± 14.65 min in the non-survivor group, while
it was 6.29 ± 2.84 min in the survivor group, and the difference between
them was statistically significant (p \textless{} 0.001). In terms of
the initial arrest rhythm (Asystole, VF, VT, PEA); there was a
statistically significant difference between the non-survivor group (n =
45, 1, 1, and 7; respectively) and the survivor group (n = 5, 6, 0, and
2; respectively) (p \textless{} 0.001) (Table III).

When comparing the non-survivor group and the survivor group in terms of
routine biochemistry and cardiac markers, the urea, creatinine,
potassium, lactate dehydrogenase (LDH), and cTn levels in the
non-survivor group (91.51 ± 58.06 mg dL-1, 2.08 ± 1.64 mg dL-1, 4.93 ±
1.22 mmol L-1, 1072.14 ± 3119.52 U L-1, and 685.39 ± 1687.14 pg mL-1,
respectively) were higher than in the survivor group (40.62 ± 20.49 mg
dL-1, 1.09 ± 0.49 mg dL-1, 3.60 ± 0.68 mmol L-1, 282.44±76.02, and 62.30
± 115.67 pg mL-1, respectively) and the differences between them were
statistically significant (p = 0.001, 0.005, 0.001, 0.010, and 0.008,
respectively). There was no statistically significant difference between
these groups in terms of other parameters (Table IV).

When comparing the non-survivor and survivor groups in terms of blood
gas parameters, the COHb, bicarbonate (HCO3) and tCO2 levels in the
non-survivor group (0.78 ± 0.53\%, 15.44 ± 5.62 mmol L-1, and 34.64 ±
12.36 mmol L-1, respectively) were lower than survivor group (1.45 ±
1.31\%, 20.14 ± 5.84 mmol L-1, and 44.76 ± 13.15, respectively), and the
difference between them was statistically significant (p = 0.022, 0.016,
and 0.017, respectively). There was no statistically significant
difference between these groups in terms of other blood gas parameters
(Table IV).

\textbf{Discussion}

Based on the unique data we have obtained from our study, we propose
that CA patients' COHb level can be a predictor for ROSC. To our
knowledge, this is the first study investigating the relationship
between ROSC and COHb and MetHb levels.

In the study by Neukamm et al. (19) investigating the impact of response
time reliability on CPR incidence and resuscitation success, 2330
patients were resuscitated in the seven different emergency medical
service (EMS) systems. In 46.7\%, spontaneous circulation could be
achieved. There were no significant differences between the centers for
the ROSC rate (42.6\% vs. 53.1\%, p = 0.32). However, survival after 24
h varied between centers (15.1\% vs 30.3\% p \textless{} 0.001).
Discharge rates were between 13.8\% and 16.6\% (p = 0.50). The ROSC and
survival rates found in the current study are compatible with the
literature.

In their study, Rohlin et al. (20) investigated the effect of CPR
duration on 30-day survival. These authors concluded that the survival
rate increased as the CPR duration period was shortened. Similarly, in
the current study, the CPR duration was significantly shorter in the
ROSC group than in the non-ROSC group. Similarly, in our study, the CPR
duration was considerably shorter in the survivor group compared to the
non-survivor group.

Gilje et al. (21) investigated the predictive value of cTn in
out-of-hospital cardiac arrest (OHCA) patients, and reported that high
cTn was an independent risk factor for mortality. Similarly, in our
study, the cTn levels were higher in the non-ROSC and non-survivor
groups compared to ROSC and survival groups.

In the systemic review by Sasson et al. (22), the predictors for
survival in CA cases were investigated. These authors concluded that the
survival rates of patients with VF and VT as the initial rhythm were
higher than in other rhythms. Similarly, in our study, the amount of VF
and VT in the initial rhythm detected in the ROSC group was higher than
in the no ROSC group. Additionally, the amount of VF and VT was higher
in the survivor group compared to the nonsurvivor group.

Melley et al. (13) evaluated patients who were hospitalized in ICU after
cardiothoracic surgery and reported that minimum COHb levels were higher
in patients who stayed in intensive care for a short time and discharged
compared to patients who died. Fazekas et al.
\textsuperscript{(18)}reported that COHb levels in patients with
mortality were significantly lower than those discharged in a
non-surgical ICU. Additionally, low COHb levels in intensive care
patients were associated with high mortality, regardless of the severity
of the disease and organ failure type. Kakavas et al. reported that low
COHb level was associated with high mortality in the study in which 159
patients were followed up in chest diseases clinic with the diagnosis of
PTE involved (11). Similarly, in the current study, the COHb levels in
the ROSC group were significantly higher compared to the non-ROSC group.
Additionally, the COHb levels of the survivor group were significantly
higher compared to the non-survivor group. CO is synthesized naturally
in the body and has a very important role in range of physiological
functions including vasodilation, angiogenesis, vascular remodeling,
protection against tissue damage, and formation of the inflammatory
response (8,9). In this current study, the low CO-Hb level in the
non-survivors may have been due to the failure to activate the
inflammatory system.

Schuerholz et al. reported that MetHb levels were associated with sepsis
severity in the intensive care unit patients (14). Kakavas et al.
reported that MetHb levels might increase in high-risk PTE patients
(11). Conversely, Uzer et al. reported no correlation between MetHb and
COHb levels and the severity of PE (17). According to our results, the
MetHb levels did not have a predictive value in terms of ROSC in CA
patients.

This was a retrospective and single-center study, subject to the
limitations in generalizability with this research design.

\textbf{Conclusions:}

The author concluded that the COHb levels in the blood gas analysis at
the time of admission could be used as a predictive marker for ROSC in
CA patients. It was also emphasized that COHb levels could be used as a
post-CPR prognostic marker for mortality prediction. In this regard, we
recommend that resuscitation teams consider the COHb level in their CPR
termination decisions. On the other hand, MetHb levels had no value as a
predictive marker for ROSC and prognostic marker for patients who
achieved ROSC. Further randomized controlled studies are needed to
confirm the current study findings.

\textbf{Financial Disclosure:} This research received no specific grant
from any funding agency in the public, commercial, or not-forprofit
sectors

\textbf{Conflict of Interest:} The Authors declare that there is no
conflict of interest.

\textbf{Author contributions}

The article concept and design were developed jointly by all authors.
All authors were involved in the data interpretation, and all provided
input in each draft of the manuscript

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\begin{longtable}[]{@{}llllll@{}}
\toprule
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table I.} Demographics of the groups.\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table I.} Demographics of the groups.\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table I.} Demographics of the groups.\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table I.} Demographics of the groups.\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table I.} Demographics of the groups.\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table I.} Demographics of the groups.\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Parameter}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Groups}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{n}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\selectlanguage{ngerman}\textbf{Mean±SD}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{95\% CI}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{p}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Age}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
135\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
72.47\selectlanguage{ngerman}±13.48\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
-4.12-2.98\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
0.695 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
106\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
73.04\selectlanguage{ngerman}±14.37\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
\textbf{Gender} \selectlanguage{polish}\textbf{(Erkek/Kadın)}\selectlanguage{english}\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
73/62\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
0.896 **\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
59/47\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{CPR duration (min)}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
134\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
14.12\selectlanguage{ngerman}±11.67\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
-37.01-(-31.27)\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{\textless{}0.001 ***}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
106\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
48.26\selectlanguage{ngerman}±10.61\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
\textbf{Initial rhythm} \textbf{(Asistoli/VF/VT/PEA)}\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
91/8/3/21\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
\textbf{0.003 **}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
95/0/0/10\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation,VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation,VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation,VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation,VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation,VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation,VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage}\tabularnewline
\bottomrule
\end{longtable}\selectlanguage{english}
\begin{longtable}[]{@{}lllll@{}}
\toprule
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Table II. Comparison of ROSC group and Non-ROSC group.}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Table II. Comparison of ROSC group and Non-ROSC group.}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Table II. Comparison of ROSC group and Non-ROSC group.}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Table II. Comparison of ROSC group and Non-ROSC group.}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Table II. Comparison of ROSC group and Non-ROSC group.}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Parameter}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Groups}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Mean} \selectlanguage{ngerman}± \textbf{SD}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{95\% CI}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{p}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{White blood cell count} \textbf{(10\textsuperscript{9} cells
mL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
13.96\selectlanguage{ngerman}±8.22\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-3.11-1.57\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.379 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
14.74\selectlanguage{ngerman}±9.64\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Hematocrit} \textbf{(\%)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
37.75\selectlanguage{ngerman}±7.47\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-2.13-2.35\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.931 *\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
37.65\selectlanguage{ngerman}±9.74\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Hemoglobin} \textbf{(g dL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
12.02\selectlanguage{ngerman}±2.65\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-0.83-0.72\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.891 *\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
12.08\selectlanguage{ngerman}±3.26\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Glucose} \textbf{(mg dL-1),}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
202.15\selectlanguage{ngerman}±96.52\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-35.15-32.94\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.075 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
203.25\selectlanguage{ngerman}±159.66\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Urea} \textbf{(mg dL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
88.6\selectlanguage{ngerman}±65.08\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-57.35-(-17.09)\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textless{}0.001 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
125.91\selectlanguage{ngerman}±88.71\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Creatinine} \textbf{(mg dL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
1.87\selectlanguage{ngerman}±1.32\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-0.99-(-0.19)\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.001 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
2.47\selectlanguage{ngerman}±1.73\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Sodium} \textbf{(mmol L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
138.64\selectlanguage{ngerman}±7.45\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-2.95-1.37\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.727 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
139.44\selectlanguage{ngerman}±9.05\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Potassium} \textbf{(mmol L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
4.69\selectlanguage{ngerman}±1.29\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-0.79-(-0.09)\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.014 *\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
5.13\selectlanguage{ngerman}±1.33\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{pH}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
7.16\selectlanguage{ngerman}±0.18\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-0.05-0.06\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.869 *\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
7.16\selectlanguage{ngerman}±0.23\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{tCO2 (mmol L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
38.66\selectlanguage{ngerman}±13.70\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-1.99-5.61\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.351 *\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
36.86\selectlanguage{ngerman}±15.31\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{PCO2} \textbf{(\%)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
50.31\selectlanguage{ngerman}±20.73\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-3.89-7.40\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.306 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
48.56\selectlanguage{ngerman}±22.06\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Lactate} \textbf{(mmol L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
8.00\selectlanguage{ngerman}±5.80\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-2.39-0.87\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.524 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
8.77\selectlanguage{ngerman}±6.73\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{HCO3} \textbf{(mmol L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
17.45\selectlanguage{ngerman}±6.32\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-1.33-2.14\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.481 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
17.05\selectlanguage{ngerman}±6.86\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{COHb (\%)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.95\selectlanguage{ngerman}±0.76\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.07-0.42\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.002 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.71\selectlanguage{ngerman}±0.57\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{MetHb (\%)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.60\selectlanguage{ngerman}±0.97\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-0.21-0.28\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.769 *\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.57\selectlanguage{ngerman}±0.89\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{INR}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.63\selectlanguage{ngerman}±1.19\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-0.23-0.36\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.465 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.57\selectlanguage{ngerman}±0.88\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Prothrombin time} \textbf{(seconds)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
19.11\selectlanguage{ngerman}±14.27\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-2.22-4.59\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.467 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
17.93\selectlanguage{ngerman}±9.35\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Troponin (pg ml-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
578.69\selectlanguage{ngerman}±1770.28\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-1012.29-227.59\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.005 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
No ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
971.05\selectlanguage{ngerman}±2674.55\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{CK (U L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
254.83\selectlanguage{ngerman}±435.26\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-269.69-50.46\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.071 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
364.45\selectlanguage{ngerman}±508.10\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{CK-MB (ng mL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
9.55\selectlanguage{ngerman}±15.39\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-12.58-1.90\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.150 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
14.89\selectlanguage{ngerman}±34.01\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{LDH(U L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
708.43\selectlanguage{ngerman}±2058.14\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-805.63-(-339.86)\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.004 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
941.32\selectlanguage{ngerman}±1829.76\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{aPTT (seconds)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
32.76\selectlanguage{ngerman}±9.61\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-3.54-3.97\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.426 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
32.54\selectlanguage{ngerman}±11.94\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{proBNP (pg mL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
7419.37\selectlanguage{ngerman}±12595.36\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-5595.97-4071.09\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.397 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
8181.80\selectlanguage{ngerman}±10068.79\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{D-dimer (mg L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
11.09\selectlanguage{ngerman}±13.15\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-23.67-1.83\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.138 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-ROSC\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
22.01\selectlanguage{ngerman}±25.35\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
CI: Confidence interval, INR: International normalized ratio, ROSC:
Return of spontaneous circulation, SD: Standard deviation * Student's
t-test ** Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
CI: Confidence interval, INR: International normalized ratio, ROSC:
Return of spontaneous circulation, SD: Standard deviation * Student's
t-test ** Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
CI: Confidence interval, INR: International normalized ratio, ROSC:
Return of spontaneous circulation, SD: Standard deviation * Student's
t-test ** Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
CI: Confidence interval, INR: International normalized ratio, ROSC:
Return of spontaneous circulation, SD: Standard deviation * Student's
t-test ** Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
CI: Confidence interval, INR: International normalized ratio, ROSC:
Return of spontaneous circulation, SD: Standard deviation * Student's
t-test ** Chi-Square test ***Mann-Whitney U test\strut
\end{minipage}\tabularnewline
\bottomrule
\end{longtable}\selectlanguage{english}
\begin{longtable}[]{@{}llllll@{}}
\toprule
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table III. Demographics of the sub-groups}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table III. Demographics of the sub-groups}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table III. Demographics of the sub-groups}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table III. Demographics of the sub-groups}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table III. Demographics of the sub-groups}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Table III. Demographics of the sub-groups}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Parameter}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Groups}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{n}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\selectlanguage{ngerman}\textbf{Mean±SD}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{95\% CI}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{p}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{Age}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
64\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
71,98\selectlanguage{ngerman}±11.95\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
4.45-20.80\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{0.025 ***}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
14\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
59.36\selectlanguage{ngerman}±20.96\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
\textbf{Gender} \selectlanguage{polish}\textbf{(Erkek/Kadın)}\selectlanguage{english}\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
34/30\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
\textbf{0.486 **}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
6/8\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{CPR duration (min)}\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
64\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
17,17\selectlanguage{ngerman}±14.65\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
3.02-18.76\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\textbf{0.000 ***}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
14\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
6.29\selectlanguage{ngerman}±2.84\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
\textbf{Initial rhythm} \textbf{(Asistoli/VF/VT/PEA)}\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
45/1/1/7\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.16\columnwidth}\raggedright\strut
\textbf{0.000 **}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
5/6/0/2\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
N/A\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation, VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation, VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation, VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation, VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation, VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.14\columnwidth}\raggedright\strut
CI: Confidence interval, CPR: Cardiopulmonary resuscitation, N/A:
Non-applicable, PEA: Pulseless electrical activity, ROSC: Return of
spontaneous circulation, SD: Standard deviation, VF: Ventricular
fibrillation, VT: Ventricular tachycardia, * Student's t-test **
Chi-Square test ***Mann-Whitney U test\strut
\end{minipage}\tabularnewline
\bottomrule
\end{longtable}\selectlanguage{english}
\begin{longtable}[]{@{}lllll@{}}
\toprule
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Table IV. Comparison of the non-survivor group and survivor
group.}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Table IV. Comparison of the non-survivor group and survivor
group.}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Table IV. Comparison of the non-survivor group and survivor
group.}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Table IV. Comparison of the non-survivor group and survivor
group.}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Table IV. Comparison of the non-survivor group and survivor
group.}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Parameter}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Groups}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Mean} \selectlanguage{ngerman}± \textbf{SD}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{95\% CI}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{p}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{White blood cell count} \textbf{(10\textsuperscript{9} cells
mL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
15.10\selectlanguage{ngerman}±9.95\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-4.24-7.34\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.847 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
13.54\selectlanguage{ngerman}±6.22\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Hematocrit} \textbf{(\%)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
38.00\selectlanguage{ngerman}±7.43\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-7.95-1.48\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.151 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
41.23\selectlanguage{ngerman}±8.40\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Hemoglobin} \textbf{(g dL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
11.92\selectlanguage{ngerman}±2.76\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-3.18-0.28\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.097 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
13.37\selectlanguage{ngerman}±2.94\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Glucose} \textbf{(mg dL-1),}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
220.77\selectlanguage{ngerman}±97.94\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-30.52-83.14\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.471 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
194.46\selectlanguage{ngerman}±58.28\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Urea} \textbf{(mg dL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
91.51\selectlanguage{ngerman}±58.06\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
18.07-83.71\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.000 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
40.62\selectlanguage{ngerman}±20.49\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Creatinine} \textbf{(mg dL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
2.08\selectlanguage{ngerman}±1.64\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.7-1.91\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.005 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.09\selectlanguage{ngerman}±0.49\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Sodium} \textbf{(mmol L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
138.42\selectlanguage{ngerman}±6.25\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-6.81-0.56\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.051 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
141.54\selectlanguage{ngerman}±4.46\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Potassium} \textbf{(mmol L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
4.93\selectlanguage{ngerman}±1.22\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.62-2.03\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.000 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
3.60\selectlanguage{ngerman}±0.68\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{pH}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
7.15\selectlanguage{ngerman}±0.20\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-0.19-0.05\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.234 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
7.22\selectlanguage{ngerman}±0.19\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{tCO2}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
34.64\selectlanguage{ngerman}±12.36\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-17.86-(-2.39\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.017 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
44.76\selectlanguage{ngerman}±13.15\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{PCO2} \textbf{(\%)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
47.12\selectlanguage{ngerman}±21.96\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-19.80-8.00\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.490 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
53.02\selectlanguage{ngerman}±24.90\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Lactate} \textbf{(mmol L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
9.49\selectlanguage{ngerman}±5.90\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-2.39-0.87\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.104 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
7.55\selectlanguage{ngerman}±7.71\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{HCO3} \textbf{(mmol L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
15.44\selectlanguage{ngerman}±5.62\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-1.93-5.80\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.016 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
20.14\selectlanguage{ngerman}±5.84\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{COHb}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.78\selectlanguage{ngerman}±0.53\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-1.12-(-0.21\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.022 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.45\selectlanguage{ngerman}±1.31\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{MetHb}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.60\selectlanguage{ngerman}±0.97\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-0.52-0.72\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.668 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.50\selectlanguage{ngerman}±1.12\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{INR}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.83\selectlanguage{ngerman}±1.50\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-0.35-1.67\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.012 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.18\selectlanguage{ngerman}±0.388\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
\textbf{Prothrombin time} \textbf{(seconds)}\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
21.98\selectlanguage{ngerman}±18.23\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
-3.65-20.99\strut
\end{minipage} & \begin{minipage}[t]{0.19\columnwidth}\raggedright\strut
0.007 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
13.31\selectlanguage{ngerman}±4.00\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{Troponin (pg ml-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
685.39\selectlanguage{ngerman}±1687.14\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-492.93-1649.10\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.008 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
62.30\selectlanguage{ngerman}±115.67\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{CK (U L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
241.52\selectlanguage{ngerman}±338.84\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-247.05-344.08\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1.000 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
193.00\selectlanguage{ngerman}±238.78\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{CK-MB (ng mL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
9.43\selectlanguage{ngerman}±16.03\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-12.78-11.24\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.469 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
10.20\selectlanguage{ngerman}±22.29\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{LDH(U L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
1072.14\selectlanguage{ngerman}±3119.52\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-1316.75-2896.14\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.010 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
282.44\selectlanguage{ngerman}±76.02\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{aPTT (seconds)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
34.98\selectlanguage{ngerman}±11.99\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-3.13-17.73\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.102 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
27.68\selectlanguage{ngerman}±7.80\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{proBNP (pg mL-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
11144.41\selectlanguage{ngerman}±17874.26\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-16486.91-37011.73\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.060 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
882.00\selectlanguage{ngerman}±876.81\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\textbf{D-dimer (mg L-1)}\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Non-survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
12.54\selectlanguage{ngerman}±14.59\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
-13.80-27.05\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
0.732 ***\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
Survivor\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
5.92\selectlanguage{ngerman}±4.47\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
CI: Confidence interval, INR: International normalized ratio, ROSC:
Return of spontaneous circulation, SD: Standard deviation * Student's
t-test ** Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
CI: Confidence interval, INR: International normalized ratio, ROSC:
Return of spontaneous circulation, SD: Standard deviation * Student's
t-test ** Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
CI: Confidence interval, INR: International normalized ratio, ROSC:
Return of spontaneous circulation, SD: Standard deviation * Student's
t-test ** Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
CI: Confidence interval, INR: International normalized ratio, ROSC:
Return of spontaneous circulation, SD: Standard deviation * Student's
t-test ** Chi-Square test ***Mann-Whitney U test\strut
\end{minipage} & \begin{minipage}[t]{0.17\columnwidth}\raggedright\strut
CI: Confidence interval, INR: International normalized ratio, ROSC:
Return of spontaneous circulation, SD: Standard deviation * Student's
t-test ** Chi-Square test ***Mann-Whitney U test\strut
\end{minipage}\tabularnewline
\bottomrule
\end{longtable}

Figure-1: Flow Chart

\textbf{Hosted file}

\verb`Figures.docx`  available at \url{https://authorea.com/users/417431/articles/524544-do-carboxyhemoglobin-and-methemoglobin-levels-predict-the-return-of-spontaneous-circulation-and-prognosis-of-cardiac-arrest-patients}

\selectlanguage{english}
\FloatBarrier
\end{document}

