The Most Frequent Grade3/4 Laboratory Abnormalities
The 5 evaluated Grade 3/4 laboratory abnormalities included: glucose increase, lymphocyte decrease, phosphate decrease, lipase increase, and ALT increase. As shown in Figure 6 (filgotinib) and Figure 7 (GS-829845), filgotinib or GS-829845 exposures (AUC0-24) were highly overlapping between subjects who experienced (black) and who did not experience (gray) the selected Grade 3/4 laboratory abnormalities up to Week 52.