Results
FC was confirmed in 20 patients by genetic testing. In the LVH group, 12
patients were classified by biopsy to have hypertrophic cardiomyopathy,
two had hypertensive heart disease, and six LVH combined with borderline
myocarditis.
Global and regional left ventricular (LV) strain was not significantly
different between groups while LA strain was significantly impaired in
FC (Left atrial reservoir strain (LASr) 19.1%±8.4 in FC and 25.6%±8.9
in LVH, p=0.009; left atrial conduction strain (LAScd) -8.4%±4.9 in FC
and -15.9%±8.4 in LVH, p<0.01). LAScd, with an area under the
curve (AUC) of 0.81 [95% confidence interval (CI) 0.66-0.96] showed
the highest diagnostic accuracy to discriminate FC. The PLSD pattern
showed an AUC of 0.49, quantification of papillary muscle hypertrophy an
AUC of 0.47.